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| 有氧运动对衰老大鼠心肌、肝脏细胞凋亡及线粒体膜电位的影响 | |
| 引用本文： | 黄志辉,刘浩,李宪航.有氧运动对衰老大鼠心肌、肝脏细胞凋亡及线粒体膜电位的影响[J].西安体育学院学报,2007,24(1):78-80,104. |
| 作者姓名： | 黄志辉 刘浩 李宪航 |
| 作者单位： | 1. 河北师范大学公共体育教学部,石家庄,050031 2. 河北师范大学职业技术学院,石家庄,050031 3. 沧县中学,河北,沧县,061025 |
| 摘 要： | 实验研究了有氧运动对于衰老大鼠肝脏和心肌细胞凋亡以及线粒体膜电位(MMP)的影响。结果显示:老年对照组(A组)心肌、肝脏细胞凋亡比率高于青年对照组(Y组),而A组心肌、肝脏MMP低于Y组。老年运动组(AE组)心肌、肝脏细胞凋亡比率均低于A组,并且其心肌MMP高于A组。结果提示,有氧运动可有效减少衰老造成的心肌和肝脏细胞过度凋亡。有氧运动维持心肌线粒体正常MMP的作用可能是其减少心肌细胞过度凋亡的机制之一。 |
| 关 键 词： | 有氧运动 衰老 细胞凋亡 线粒体膜电位 |
| 文章编号： | 1001-747X（2007）01-0078-03 |
| 修稿时间： | 2006-03-102006-06-12 |
Effect of Aerobic Exercise on Apoptosis and Mitochondria Membrane Potential of the Heart and Liver of Aged Rats |
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| HUANG Zhi-hui,LIU Hao,LI Xian-hang.Effect of Aerobic Exercise on Apoptosis and Mitochondria Membrane Potential of the Heart and Liver of Aged Rats[J].Journal of Xi'an Institute of Physical Education,2007,24(1):78-80,104. | |
| Authors: | HUANG Zhi-hui LIU Hao LI Xian-hang |
| Institution: | 1. a, Public PE. Department; b. Professional Technique Institute, Hebei Normal University, Shijiazhuang 050031, China;2. Cangxian Middle School, Cangxian 061025, China |
| Abstract: | The authors studied the effects of aerobic exercise on the apoptosis and mitochondria membrane potential(MMP) of the liver and heart of aged rats.The results show that the apoptosis rate in the heart and liver of Aged Group(A Group)is higher than that of Young Group(Y Group) while the MMP of heart and liver cell of A Group is lower than that of Y Group.The apoptosis rate of Aged and Exercise Group(AE Group) is lower than that of A Group and the MMP of heart cell of AE Group is higher than that of A Group.These results indicate that aerobic exercise can reduce the excessive apoptosis of heart and liver resulted from the aging process.The effect of maintaining the normal MMP of heart cell may be a reason why aerobic exercise can reduce the excessive apoptosis of heart cell of aged rats. |
| Keywords: | aerobic exercise aging apoptosis mitochondria membrane potential |
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