Correlation between serum lipid profile and carotid intima-media thickness in Polycystic Ovarian Syndrome |
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| Authors: | Sarama Saha Chandan Sarkar Subhash Chandra Biswas R Karim |
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| Institution: | (1) Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Patras Medical School, 26500 Patras, Greece;(2) Department of Obstetrics and Gynecology, University of Patras Medical School, 26500 Patras, Greece; |
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| Abstract: | Abnormal lipid profile is often found in women with Polycystic Ovary Syndrome. To assess the impact of abnormal lipid profile
on atherosclerosis in young Polycystic Ovary Syndrome women, carotid intima-media thickness as judged by B-mode ultrasonography
were done in 30 young (18–35 yrs) Polycystic Ovary Syndrome women and in similarly age-matched 30 apparently healthy controls.
Compared to controls, young Polycystic Ovary Syndrome women had significantly elevated serum total cholesterol, triglyceride
and LDL-C levels and carotid intima-media thickness. HDL-C level did not differ significantly between two groups of women.
In Polycystic Ovary Syndrome women carotid intima-media thickness was positively correlated with serum total cholesterol,
triglyceride and LDL-C and negatively correlated with serum HDL-C. Our study suggests that even young Polycystic Ovary Syndrome
women are prone to atherosclerosis from early age. |
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| Keywords: | Lipid Profile Polycystic Ovary Syndrome Carotid Intima-media thickness |
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