| 奥扎格雷钠联合黄芪注射液治疗糖尿病肾病的疗效观察 |
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| 引用本文： | 孙志刚,董建芳,孙海鹏.奥扎格雷钠联合黄芪注射液治疗糖尿病肾病的疗效观察[J].河北北方学院学报(医学版),2006,23(3):28-29. |
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| 作者姓名： | 孙志刚 董建芳 孙海鹏 |
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| 作者单位： | 河北北方学院附属第三医院肾内科,河北,张家口,075000 |
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| 摘 要： | 目的：观察奥扎格雷钠与黄芪注射液联合治疗糖尿病肾病的疗效。方法：将84例早期糖尿病肾病患者随机分为3组，每组28例，在常规治疗的基础上，A组加用黄芪注射液，B组加用奥扎格雷钠注射液，C组加用黄芪注射液与奥扎格雷钠注射液，疗程均为20d。观察治疗前后各组尿白蛋白排泄率（UAER），血尿素氮（BUN），血清肌酐（SCr），糖化血红蛋白（HbAlc）的变化。结果：糖化血红蛋白，血清肌酐，血尿素氮，尿白蛋白排泄取：3组治疗后均比治疗前显著下降（P〈0．01），C组下降幅度优于A组和B组（P〈0．05）。结论：奥扎格雷钠联合黄芪注射液治疗糖尿病肾病能降低糖化血红蛋白，显著降低尿白蛋白排泄率，同时改善肾功能。
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| 关 键 词： | 黄芪注射液 奥扎格雷钠 糖尿病肾病 |
| 文章编号： | 1673-1484（2006）03-0028-02 |
Clinical Observation on the Treatment for Early Diabetic Nephropathy by Aozhagelei Injection Combined with Milkvetch Injection |
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| SUN Zhi-gang,DONG Jian-fang,SUN Hai-peng.Clinical Observation on the Treatment for Early Diabetic Nephropathy by Aozhagelei Injection Combined with Milkvetch Injection[J].Journal of Hebei North University:Medical Edition,2006,23(3):28-29. |
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| Authors: | SUN Zhi-gang DONG Jian-fang SUN Hai-peng |
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| Institution: | The Third Affiliated Hospital Hebei North University,Zhangjiakou,075000, Hebei China |
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| Abstract: | Objective:To investigate the therapeutic effect of mickvetch injection(MI) combined with Aozhagelei injection on earlydiabetic nephropathy(EDN).Methods:84 patients with EDN were randomly divided into three groups,with 28 in each groups.After conventional hypoglycemic therapy for the patients in all groups,patients in group A were treated with MI,for group B with Aozhagelei injection and group C with Aozhagelei plus MI respectively.The therapeutic course for all patients was 3 weeks.The related indices of EDN before and after treatment were determined and compared,including blood urea nitrogen(BUN),Serum creatinine(SCr),urinary albumin excretion rates(UAER)and,HbAlc.Results:the levels of BUN,SCr,HbAlc,and UAER were significantly decreased in all 3groups(P<0.01).and the decreasement in Group C was more significant than that of the other two groups(P<0.05).Conclution:Aozhagelei injection combined with MI can decrease HbAlc,and UAER significantly in treating EDN and can improve kidney function. |
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| Keywords: | Aozhagelei injection Milkvetch injection Diabetic nephropathy |
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