Preliminary studies on the hypoglycaemic effect ofAbroma augusta in alloxan diabetic rats |
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| Authors: | Halim Eshrat M Ali Hussain Kaiser Jamil Mala Rao |
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| Institution: | (1) National Chemical Laboratory, 411008 Pune;(2) Indian Institute of Chemical Technology, 500007 Hyderabad |
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| Abstract: | The hypoglycemic effect of the aqueous extract ofAbroma augusta (Family: Steculiceae) was studied in normal as well as alloxan diabetic rats. Treatement of diabetic rats with 4 ml (4gm
dry weight) of agueous extract ofA. augusta for 16 weeks resulted in gradual but significant fall in fasting blood glucose and improvement in glucose tolerance. Serum
total and LDL cholesterol and triacylglycerol which increased in diabetic rats showed improvement. These results show that
the water extract ofA. augusta has both hypoglycemic and hypocholesterolemic effects. |
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| Keywords: | Abroma augusta diabetes mellitus hypoglycemic effect hypolipidemic effect |
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