Accumbens D2: Raters of the Loss Outcome |
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| Authors: | Andrew T Marshall Kimberly Kirkpatrick |
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| Institution: | 1.Department of Psychological Sciences,Kansas State University,Manhattan,USA |
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| Abstract: | Zalocusky et al. (Nature 531:642–646, 2016) recently showed that activity in D2R+ cells in the nucleus accumbens is associated with loss sensitivity to prior outcomes and reduced subsequent risky choice, and that optogenetic stimulation of these cells decreased risky choices in risk-prone rats. While their findings are important for understanding trait-level risk-taking, future research should aim to examine the neuronal mechanisms of a broader range of facets of gain and loss processing with respect to different potential reference points. |
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