Dyslipidaemia Associated with Type 2 Diabetics with Micro and Macrovascular Complications among Ghanaians |
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| Authors: | Michael B Adinortey Ben E Gyan Jonathan Adjimani Philomena Nyarko Charity Sarpong Francis Y Tsikata Alexander K Nyarko |
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| Institution: | (1) Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana;(2) Immunology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana;(3) Department of Biochemistry, University of Ghana, Legon, Ghana;(4) Regional Institute for Population Studies, University of Ghana, Legon, Ghana;(5) Tema General Hospital, Ghana Health Service, Tema, Ghana;(6) Clinical Pathology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana |
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| Abstract: | In this study, differences in lipid levels amongst diabetics with and without complications were assessed to determine lipid
disorders that are associated with diabetic complications other than cardiovascular diseases. A Cross sectional study design
was employed. The study included 288 diabetics and 108 non diabetics with different types of complications such as hypertension,
nephropathy, neuropathy, and retinopathy. The mean serum total cholesterol was higher in patients with complications compared
to those without complications and the non-diabetic controls. The normotensive diabetic patients had the lowest total cholesterol
among the diabetic patients’ groups (4.65 ± 0.17 mmol/l) compared to the diabetics with hypertension (6.051 ± 0.20 mmol/l),
retinopathy (6.26 ± 0.29 mmol/l), neuropathy (5.80 ± 0.17 mmol/l) and nephropathy patients 5.74 ± 0.26 mmol/l (P < 0.05). The prevalence of dyslipidaemia among diabetic subjects was between 19.2 and 84.0%. The study shows that, in addition
to macrovascular complications, dyslipidaemia is common in type 2 diabetes mellitus patients with microvascular complications. |
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| Keywords: | Type 2 diabetes mellitus Ghanaians Dyslipidaemia Complications |
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