| 鸡血藤水提物的镇静、催眠作用研究 |
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| 引用本文： | 黄新炜,李宝强,王秀华,邵爱东.鸡血藤水提物的镇静、催眠作用研究[J].西安文理学院学报,2009,12(1):62-64. |
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| 作者姓名： | 黄新炜 李宝强 王秀华 邵爱东 |
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| 作者单位： | 黄新炜,HUNAG Xin-wei(西安文理学院,化学系,陕西,西安,710065);李宝强,LI Bao-qiang(戴安中国有限公司,北京,100029);王秀华,WANG Xiu-hua(北京康倍得医药技术开发有限公司,北京,100089);邵爱东,SHAO Ai-dong(中国人民解放军第三医院,传染科,陕西,宝鸡,721004)
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| 基金项目： | 西安文理学院专项科研基金 |
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| 摘 要： | 初步探讨了采用镇静、催眠实验观察鸡血藤水提物对小鼠自主活动的影响以及协同戊巴比妥钠对小鼠的催眠作用以鸡血藤水提物的镇静、催眠药理作用．显示鸡血藤水提物能明显减少小鼠自主活动次数，增加阈下剂量戊巴比妥钠致小鼠睡眠只数，延长阈上剂量戊巴比妥钠致小鼠睡眠时间．结果表明鸡血藤水提物具有明显的镇静、催眠作用．
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| 关 键 词： | 鸡血藤 镇静 催眠 |
Studies on the Sedative and Hypnotic Effects of the Water Extract of Spatholobus Suberectus Dunn. |
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| HUNAG Xin-wei,LI Bao-qiang,WANG Xiu-hua,SHAO Ai-dong.Studies on the Sedative and Hypnotic Effects of the Water Extract of Spatholobus Suberectus Dunn.[J].Journal of Xi‘an University of Arts & Science:Natural Science Edition,2009,12(1):62-64. |
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| Authors: | HUNAG Xin-wei LI Bao-qiang WANG Xiu-hua SHAO Ai-dong |
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| Institution: | 1. Department of Chemistry, Xi＇an College of Arts and Science, Xi＇an 710065, China; 2. Dionex China Ltd, Beijing 100029, China; 3. Beijing KangBeide pharmaceuticals Co. Ltd, Beijing 100089, China; 4. Department of Infectious Disease, The Third Hospital of PLA, Baoji 721004, China) |
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| Abstract: | To make a preliminary study on the sedative and hypnotic effects of the water extract of Spatholobus suberectus Dunn. Sedative and hypnotic experiments were made to observe the effects of the water extract of Spatholobus suberectus Dunn on spontaneous motion and hypnosis in mice. The results showed that the water extract of Spatholobus suberectus Dunn could markedly inhibit spontaneous motion, enhance the sleeping number of pentobarbital sodium （ subthreshold dosage） and prolong the sleeping time of pentobarbital sodium （ superthreshold dosage）. The water extract of Spatholobus suberectus Dunn possesses obvious sedative and hypnotic effects. |
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| Keywords: | spatholobus suberectus dunn sedation hypnotism |
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