Place of salivary β glucuronidase activity in head & neck cancers |
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| Authors: | M S Ghadge A S Raste |
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| Institution: | (1) Department of Biochemistry, Tata Memorial Hospital, 5th floor, Annexe Building, Dr. E. Borges Marg, Parel, 400012 Mumbai |
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| Abstract: | Salivary β-glucuronidase activity was studied in 20 healthy subjects without habits and 10 with habits, 38 untreated patients
of advanced head and neck cancer and 21 patients after treatment either after surgery or radiation.
Salivary β-glucuronidase activity was elevated in untreated cases of head and neck cancer (p<0.001), with a fall in the activity
after treatment. The post operative fall in the activity of salivary β-glucuronidase activity was highly significant (p<0.001)
as compared to post radiation. This test can be utilized in the diagnosis and also for monitoring the course of the disease. |
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