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运动减肥对肥胖儿童少年红细胞膜磷脂酰丝氨酸外翻及ATPase酶活性的影响
引用本文:赖爱萍,陈文鹤.运动减肥对肥胖儿童少年红细胞膜磷脂酰丝氨酸外翻及ATPase酶活性的影响[J].中国体育科技,2011,47(5).
作者姓名:赖爱萍  陈文鹤
作者单位:1. 浙江体育职业技术学院体育系,浙江 杭州,310012
2. 上海体育学院运动科学学院,上海,200438
基金项目:上海市第三期运动人体科学重点学科开放基金课题(No:S30902); 浙江省教育厅科研项目(Y200909098)
摘    要:目的:探讨肥胖儿童少年红细胞膜PS外翻水平和ATP酶活性及运动减肥干预对其的影响.方法:对64名肥胖儿童少年(按体脂百分比分为轻、中和重度肥胖组共3组)进行4周有氧运动减肥,采用流式细胞术测定红细胞膜PS外翻,干预前后进行血脂、PS外翻及Na K+ - ATPase和Ca2+ Mg2+- ATPase酶活性的测定.结果:运动干预前轻度肥胖组PS外翻与其他2组肥胖者之间存在显著性差异(P≤0.05),HDL仅在轻度组和重度组之间存在显著性差异;运动干预后Na+ K+ -ATPase活性显著增加(P≤0.05),CE2+ Mg2+- ATPase活性虽有增加,但未呈显著性水平;运动干预后PS外翻虽然有所下降,但无显著性差异.结论:脂代谢紊乱的初期,膜PS外翻可能比血脂指标更能体现肥胖的发展.有氧运动减肥能显著增加红细胞膜Na+ K+ - ATPase活性,改善红细胞膜PS外翻水平,但后者对运动干预的效应滞后于血脂变化.

关 键 词:肥胖  儿童  少年  红细胞膜磷脂酰丝氨酸外翻  ATPase酶活性

Influence of Exercise-induced Weight Loss on Erythrocyte Membrane Phosphatidylserine Exposure and ATPase Activity in Obese Children and Adolescents
LAI Ai-ping,CHEN Wen-he.Influence of Exercise-induced Weight Loss on Erythrocyte Membrane Phosphatidylserine Exposure and ATPase Activity in Obese Children and Adolescents[J].China Sport Science and Technology,2011,47(5).
Authors:LAI Ai-ping  CHEN Wen-he
Institution:LAI Ai-ping1,CHEN Wen-he21.Zhejiang College of Sports,Hangzhou 310012,China,2.School of Kinesiology,Shanghai University of Sport,Shanghai 200438,China.
Abstract:Objective:To evaluate erythrocyte membrane PS exposure and ATPase activity in obese children and adolescents,and investigate the influence of exercise-induced weight loss on them.Methods:64 obese children and adolescents(divided into mild,moderate and severe obesity group according to percentage of body fat) completed a 4 weeks aerobic exercise program to lose weight.PS exposure on erythrocyte membrane was performed by flow cytometry.Plasmalipids,PS exposure,Na+K+-ATPase and Ca2+Mg2+-ATPase before and after...
Keywords:obese  children  adolescents  erythrocyte membrane phosphatidylserine exposure  ATPase activity  
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