| 幼鼠膈肌损伤与漏斗胸发生的实验研究 |
| |
| 引用本文： | 严文静,吴学东,李俊.幼鼠膈肌损伤与漏斗胸发生的实验研究[J].大理师专学报,2013(6):27-30. |
| |
| 作者姓名： | 严文静 吴学东 李俊 |
| |
| 作者单位： | [1]大理学院护理学院,云南大理671000 [2]大理学院附属医院,云南大理671000 |
| |
| 摘 要： | 目的：探讨幼鼠膈肌损伤后与漏斗胸（PE）发生的关系。方法：将40NSD大鼠分成2组，实验组造成人为膈肌损伤，对照组施以假手术，至鼠龄12周全部处死观察胸廓外观及膈肌组织学形态。结果：膈肌损伤后，动物PE发生率为38．89％（7／18），实验组动物PE的发生率与对照组比较，差异有统计学意义。膈肌损伤后组织愈合结果为肌纤维结构松散、部分肌组织萎缩，纤维结缔组织增生，瘢痕形成。结论：膈肌损伤后瘢痕愈合引起膈肌挛缩，挛缩的膈肌持续牵拉前胸壁，牵拉力量是导致大鼠PE发生的主要因素之一。
|
| 关 键 词： | 膈肌损伤 漏斗胸 实验研究 SD大鼠 |
Experimental Study of the Pectus Excavatum after Diaphragm Injury in Juvenile Rats |
| |
| YAN Wenjing,WU Xuedong,LI Jun.Experimental Study of the Pectus Excavatum after Diaphragm Injury in Juvenile Rats[J].Journal of Dali Teachers College,2013(6):27-30. |
| |
| Authors: | YAN Wenjing WU Xuedong LI Jun |
| |
| Institution: | 2. ( 1.College of Nursing, Dali University, Dali, Yunnan 671000, China; 2.Affiliated Hospital of Dali University, Dali, Yunnan 671000, China) |
| |
| Abstract: | Objective： To study the relationship of diaphragmatic injury and pectus excavatum in rats. Methods： Forty SD rats were divided into 2 groups, intervene group received the operation of injury diaphragm, and the control group received the sham operation. At the age of 12 weeks, all rats were sacrificed for observations of the chest appearance and histology and morphology of diaphragm. Results： The incidence rate of the pectus excavatum in intervened SD rats was 38.89% （7/18） after diaphragm contracture. Compared to the control group, the incidence rates were different with statistic significance. The muscle fiber structure was loose and disordered; the muscular atrophy, hyperplasia of fibrous connective tissue and scar formation were found in diaphragm injure. Conclusion： Injuried diaphragm led to contracture after diaphragm cicat,＇icle healing, the contracture of diaphragm created a continuous stretch power on anterior chest wall, the force may be one of the factors which induce pectus excavatum. |
| |
| Keywords: | diaphragm injury pectus excavatum experimental research SD rats |
| 本文献已被 维普 等数据库收录！ |
|
