| 蛋白质芯片技术及生物医学应用 |
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| 引用本文： | 靳刚.蛋白质芯片技术及生物医学应用[J].中国科学院院刊,2003,18(5):362-364,361. |
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| 作者姓名： | 靳刚 |
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| 作者单位： | 力学研究所,北京,100080 |
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| 摘 要： | 蛋白质芯片技术是一种新型蛋白质分析技术。文章介绍了研究它的目的和意义,重点介绍它的研制过程和研究内容以及生物医学应用。
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| 关 键 词： | 蛋白质芯片 蛋白质分析 椭偏成像 表面改性 |
| 修稿时间： | 2003年7月26日 |
Protein Chip Technique and Its Bio-medical Applications |
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| Jin Gang.Protein Chip Technique and Its Bio-medical Applications[J].Bulletin of the Chinese Academy of Sciences,2003,18(5):362-364,361. |
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| Authors: | Jin Gang |
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| Institution: | Institute of Mechanics, CAS, 100080 Beijing |
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| Abstract: | Based on the biosensor concept with imaging ellipsometry, the proteinchip was developed as a new technique for protein analysis. The chip in micro-array was patterned with multi-bioactivity of proteins. The chip could be used for protein detection, identification and purification as well as protein interaction with only a little sample consumption and labeling free. It's able directly to test raw physiological samples such as serum, urine, sputum, adnoid liquid, and splitted cell solution, etc. Its high spatial resolution and high throughout might be available to perform multi-analysis simultaneously with high speed and repeatability for clinic diagnosis, medicine screening and protein function analysis. |
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| Keywords: | protein chip protein analysis imaging ellipsometry surface modification |
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