Comparison of high order aberration after conventional and customized ablation in myopic LASIK in different eyes of the same patient |
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| Authors: | Du Chi-xin Shen Ye Wang Yang |
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| Institution: | (1) Department of Ophthalmology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China |
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| Abstract: | Purpose: To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK (laser in
situ keratomileusis) with conventional ablation and customized ablation in different eyes of the same patient. Methods: This
was a prospective randomized study of 54 myopic eyes (27 patients) that underwent LASIK using the Nidek EC-5000 excimer laser
system (Nidek, Gamagori, Japan). Topography-guided customized aspheric treatment zone (CATz) was used in the first eye of
the patient (study group) and the other eye of the same patient was operated on with conventional ablation (control group).
Higher order aberrations root-mean-square (RMS) in the 5-mm zone] of both groups were observed with the Nidek OPD-Scan aberrometer
before and 3 months after LASIK. Preoperative mean refractive error was similar between two eyes of the same patient (t=−0.577, P>0.05). Results: Preoperatively, higher order aberrations (RMS in the 5-mm zone) in the CATz ablation and conventional groups
were (0.3600±0.0341) μm and (0.2680±0.1421) μm, respectively. This difference was not statistically significant (t=1.292, P>0.05). Three months after LASIK, higher order aberrations (RMS in 5-mm zone) in the CATz ablation and conventional groups
were (0.3627±0.1510) μm and (0.3991±0.1582) μm, respectively. No statistically significant difference was noted between pre-and
postoperative higher order aberrations in the CATz group (t=−0.047, P>0.05). However, a statistically significant increase in higher order aberrations was observed after conventional ablation
(t=−5.261, P<0.05). A statistically significant difference was noted in the increase of higher order aberrations after LASIK between groups
(t=−2.050, P=0.045). Conclusion: LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA (best
spectacle-corrected visual acuity) 3 month after LASIK. Higher order aberrations were increased, but the increase of higher
order aberrations after customized ablation treatment was less than that after conventional ablation.
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| Keywords: | Myopic LASIK (laser in situ keratomileusis) Higher order aberrations Customized ablation |
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