| 344例ⅠⅡ期乳癌的远期疗效观察 |
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| 引用本文： | 杨东东,安永铸,雷杰,屈明,张迎春,张振忠.344例ⅠⅡ期乳癌的远期疗效观察[J].河北北方学院学报(医学版),1997(5). |
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| 作者姓名： | 杨东东 安永铸 雷杰 屈明 张迎春 张振忠 |
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| 作者单位： | 张家口医学院一附院 075029
(杨东东，安永铸，雷杰，屈明，张迎春)，张家口医学院一附院 075029(张振忠) |
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| 摘 要： | 作者随访334例临床ⅠⅡ期乳癌,结果提示:临床ⅠⅡ期乳癌无论采用传统根治或改良根治术,其5、10年生存率无差别;但单纯改良根治术后5年复发率高于传统根治术;放疗加化疗确能提高手术后(特别是改良根治术后)5年生存率,降低5年内复发率;手术后早期放疗和/或化疗不能改善10年生存率,降低10年复发率。因此,作者认为术后无条件行化疗和放疗的乳癌患者,尽可能行传统乳癌根治术。并强调手术后特别是改良根治术后放疗加化疗的必要性。生存5年以上的患者应定期化疗,局部复发或有远处转移者应结合手术行再放疗以提高10年生存率,降低10年复发率。
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| 关 键 词： | 乳癌 手术 放疗 化疗 生存率 复发率 |
Investigation of 344 cases of patients with stage I . II breast cancer |
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| Yangdongdong,Anyunzhu,Leijie,Quming,Zhangyengchun,Zhangzhezhong..Investigation of 344 cases of patients with stage I . II breast cancer[J].Journal of Hebei North University:Medical Edition,1997(5). |
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| Authors: | Yangdongdong Anyunzhu Leijie Quming Zhangyengchun Zhangzhezhong |
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| Abstract: | 344 coses of patients with stage I . II breast cancer are investigated by author and covjorkers. Our results indicate that the five - year and ten - year survival rates (65% , 32. 5% ) of stage I . II breastcancer patients treated with radical mastectomy(RM) have no significantdifference in comparison with those( 58. 33% , 23. 81% ) of the patientstreated with modified radical mastectomy (MRM); the five - year recurrentrate(62. 5% ) of the patients treated with MRM is higher than that( 35% ) ofthe patients treated -with RM; combination of post ~ operativechemotherapy and radiotherapy can in crease the five - year survival rate, and decrease the five - year recurrent rate, of the patients treatedivith MRM of RM; simple chemotherapy or radiotherapy can also leaver theffive year recurrent rate of the patients treated with MRM; however, early post - operative chemotherapy and I or radiotherapy fail to improvethe ten - year survival rale, and decrease the ten - year recurrent rate, of the patients treated with MRM of RM. Therefor, author emphases theimportance of post ~ operative chemotherapy and I or radiotherapy to thepatients with stage I . II breast cancer ', if post - operative chemotherapyand / or radiotherapy cannot be administered, radical mastectomy( RM) isproposed', moreover, periodic chemotherapy and I oar radiotherapy afterearly treatment ma improve the ten - year survival rate, and lower theten - year recurren rate, of the patients with stage I . II breast cancer. |
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| Keywords: | Breast cancer Operation Chemotherapy Radiotherapysurui-val rate Recurrent rate |
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