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Individual Differences in the Stability and Change of Childhood Depression: A Growth Mixture Model With Structured Residuals
Authors:Matt Hawrilenko  Katherine E Masyn  Janine Cerutti  Erin C Dunn
Institution:1. University of Washington School of Medicine;2. Georgia, State University;3. Massachusetts General Hospital
Abstract:Studies of developmental trajectories of depression are important for understanding depression etiology. Existing studies have been limited by short time frames and no studies have explored a key factor: differential patterns of responding to life events. This article introduces a novel analytic technique, growth mixture modeling with structured residuals, to examine the course of youth depression in a large, prospective cohort (N = 11,641, ages 4–16.5, 96% White). Age-specific critical points were identified at ages 8 and 13 where depression symptoms spiked for a minority of children. Most depression risk was due to dynamic responses to environmental events, drawn not from a small pool of persistently depressed children, but a larger pool of children who varied across higher and lower symptom levels.
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