| 青石斑鱼对创伤弧菌粗制脂多糖的免疫学反应 |
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| 引用本文： | 秦启伟,潘金培.青石斑鱼对创伤弧菌粗制脂多糖的免疫学反应[J].中山大学学报论丛,1995(3). |
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| 作者姓名： | 秦启伟 潘金培 |
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| 作者单位： | 中国科学院南海海洋研究所!广州510301 |
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| 基金项目： | 广东省自然科学基金!930681 |
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| 摘 要： | 从石斑鱼弧菌病病原创伤弧菌中提取出粗制脂多糖（LPS）加热去毒后注射免疫石斑鱼，鱼体在较短时间（7d）内快速产生体液免疫应答，应答期在56d以上．攻毒感染后，免疫鱼显示出较强的保护功能．二次免疫效果较好
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| 关 键 词： | 青石斑鱼 创伤弧菌粗制脂多糖 免疫 |
The Immune Response of Epinephelus awoara to Vibrio vulnificus Crude Lipopolysaccharide |
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| Qin Qiwei,Pan Jinpei.The Immune Response of Epinephelus awoara to Vibrio vulnificus Crude Lipopolysaccharide[J].Supplement to the Journal of Sun Yatsen University,1995(3). |
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| Authors: | Qin Qiwei Pan Jinpei |
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| Abstract: | The crude lipopolysaccharide (LPS) was extracted from pathogenic Vibrio vulnificus of Epinephelus awoara. The crude LPS was heated to reduce its toxicity. Fish were immunized with crude LPS by a single or two times intraperitoneal injection. Antibodies produced more quickly against V. vulnificus and serum agglutination antibodies reached maximum titres after 28 days when the first injection was given in E. awoara. Fish Were challenged with live pathogenic V. vulnificus 35 days and 56 days after the first immunization,all vaccinations were highly effective to against the experimental challenge, two times immunized fish was more effective. |
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| Keywords: | Grouper Epinephelus awoara Vibrio vulnifcus crude lipopolysaccharide immunization |
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