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血浆中粉防己碱和防己诺林碱提取方法的比较研究
引用本文:杨彩玲,陈宏彬,张鸣.血浆中粉防己碱和防己诺林碱提取方法的比较研究[J].甘肃高师学报,2009,14(2).
作者姓名:杨彩玲  陈宏彬  张鸣
作者单位:兰州城市学院,化学与环境科学学院,甘肃兰州,730070
摘    要:利用液相微萃取(LPME)方法对人血浆中粉防己碱和防己诺林碱进行提取,重点考察了液相微萃取的最优条件,并从提取效率、净化能力、提取成本和绿色环保等方面分别与液-液萃取、固相萃取和蛋白质沉淀的方法进行了比较.

关 键 词:液相微萃取  固相萃取  蛋白质沉淀  HPLC  粉防己碱  防己诺林碱  人血浆

Comparing and Research on the Extraction method of Tetrandrine and Fangchinoline in Human Plasma
YANG Cai-ling,CHEN Hong-bing,ZHANG Ming.Comparing and Research on the Extraction method of Tetrandrine and Fangchinoline in Human Plasma[J].Journal of Gansu Normal College,2009,14(2).
Authors:YANG Cai-ling  CHEN Hong-bing  ZHANG Ming
Institution:College of Chemistry and Environmental Science;Lanzhou City University;Lanzhou Gansu 730070
Abstract:Tetrandrineand and fangchinoline in human plasma were extracted using liquid-phase microextraction(LPME) technology.Several parameters influencing the efficiency of LPME were investigated and optimized including organic solvent,stirring rate,extrac-tion time,salt concentration,organic modifier and pH,and the extraction methods for liquid-phase microextraction,liquid-liquid ex-traction,protein precipitation and solid-phase extraction were compared from four aspects including extraction efficiency,clean-up ca...
Keywords:HPLC
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