| 高温预处理和室温不同强度对大鼠肾脏热休克蛋白70（HSP70）表达的影响 |
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| 引用本文： | 吴明飞,肖国强.高温预处理和室温不同强度对大鼠肾脏热休克蛋白70（HSP70）表达的影响[J].辽宁体育科技,2008,30(6):30-32. |
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| 作者姓名： | 吴明飞 肖国强 |
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| 作者单位： | 华南师范大学体育科学院,广东,广州,510006 |
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| 摘 要： | 研究目的：探讨高温预处理室温下不同强度对肾脏HSP70表达的影响以及肾脏线粒体抗氧化系统SOD和脂质过氧化MDA等的变化。方法：3月龄SD雄性大鼠48只随机分为室温安静组、室温15m/min组、室温27m／min组、预处理安静组、顸处理15m／min组、预处理27m/min组。高温预处理组（高温应激直肠温度达到42℃，持续15min）预处理24h后进行实验。安静组在安静状态下、运动组在运动后即刻麻醉处死取材。结果：（1）肾脏HSPT0随运动强度增加表达增高，预处理组肾脏HSP70显著高于对应的室温组（P〈0．05）；（2）高温预处理组肾脏线粒体丙二醛（MDA）含量均低于对应的室温组；超氧化物歧化酶（SOD）活性均高于对应的室温组。结论：高温预处理可以促进运动中肾脏HSP70的表达；提高了肾脏对运动中自由基损伤的应激能力。
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| 关 键 词： | 高温预处理 热休克蛋白 肾脏 |
Effect of different intensifies on the expression of heat shock protein 70 in kidney after high temperature treatment in normal condition |
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| WU Ming-fei,XIAO Guo-qing.Effect of different intensifies on the expression of heat shock protein 70 in kidney after high temperature treatment in normal condition[J].Liaoning Sport Science and Technology,2008,30(6):30-32. |
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| Authors: | WU Ming-fei XIAO Guo-qing |
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| Institution: | WU Ming-fei, XIAO Guo-qing (Sports science college of Hunan Normal universtity, Guongzhou Guangdong 510006) |
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| Abstract: | Objective: This paper is to probe effect of different intensities on the expression of HSP70 in kidney in normal condition after high temperature treatment,to observe the changes of SOD,MDA. Conclusion:High temperature treatment can enhance the expression of HSP70 in kidney and enhance renal responsion to damage of free radical in running. |
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| Keywords: | high temperature treatment heat shock protein kidney |
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