| rLent／NT4-NAP及运动对AD模型大鼠的影响 |
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| 引用本文： | 张晓华,李世昌.rLent／NT4-NAP及运动对AD模型大鼠的影响[J].体育科技文献通报,2010,18(11):121-122. |
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| 作者姓名： | 张晓华 李世昌 |
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| 作者单位： | 华东师范大学体育与健康学院,上海,200241 |
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| 摘 要： | 阿尔茨海默病（Mzheimer disease，AD）是一种常见的老年性痴呆症，由于神经元丧失以及神经递质的缺少导致各种认识和认知功能障碍。神经保护肽慢病毒（rLent／NT4-NAP）感染AD大鼠鼻黏膜后能够分泌表达神经保护肽（NAP），NAP能抑制细胞凋亡，对AD产生保护作用。运动可以对AD大鼠产生有利影响，从而延缓AD大鼠病情。本文采用综述的办法，详细介绍了rLent／NT4-NAP和运动对AD模型大鼠的影响。通过以上论述。为预防、减缓和治疗AD提供相关理论依据。
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| 关 键 词： | 阿尔茨海默病 神经保护肽慢病毒 神经保护肽 运动 |
Impact of rLent/NT4-NAP and Exercise on the AD Mice |
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| ZHANG Xiao- hua,LI Shi-chang.Impact of rLent/NT4-NAP and Exercise on the AD Mice[J].Bulletin of Sport Science & Technology,2010,18(11):121-122. |
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| Authors: | ZHANG Xiao- hua LI Shi-chang |
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| Institution: | ZHANG Xiao - hua, LI Shi -chang( College of Physical Education and Health, East China Normal University, Shanghai 200241 ,China.) |
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| Abstract: | Alzheimer disease is a kind of common Alzheimer＇ s disease, because of neurons missing and the lack of the neurotransmitter lead to a variety of cognitive and cognitive dysfunction, rLent/NT4 - NAP infect AD mice after nasal secretion of the expression of NAP, NAP can inhibit cell apoptosis, have a protective effect on AD. Exercise can have a benefit impact on AD mice, may mitigate the disease in AD mice. This article discusses the effects of rLent/NT4 - NAP and exercise on AD mice and provide a scientific theory for the prevention, mitigation and treatment of AD. |
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| Keywords: | AD rLent/NT4- NAP NAP exercise |
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