Malignant peritoneal mesothelioma presenting with persistent high fever |
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| Authors: | Chen Li-ying Huang Ling-xiu Wang Jin Qian Yi Fang Li-zheng |
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| Institution: | (1) Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Room L1-245, P. O. BOX 22660, 1100DD Amsterdam, The Netherlands;(2) Academic Medical Center, Emma Children’s Hospital, University of Amsterdam, 1100DD Amsterdam, The Netherlands |
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| Abstract: | Malignant peritoneal mesothelioma (MPM) is a rare tumor that develops in the peritoneum. In this paper, we describe an extremely
rare case of MPM metastasizing to the appendix in a 48-year-old female who initially presented with a persistent high fever.
The woman reported a slight lower abdominal discomfort which had been relieved by urination for four months. She had lost
5 kg of weight. There was no nausea, vomiting, diarrhea, abdominal pain, or abdominal distension. Many broad spectrum antibiotics
were given without relief of fever. Computed tomography (CT) scans revealed a thickened omentum majus and diffused multiple
omental nodules. An omentectomy, appendectomy, and adnexectomy were carried out. A gross pathologic specimen of omentum tissue
revealed a firm gray-white mass. Microscopic and immunohistochemical examinations confirmed the diagnosis of appendiceal and
bilateral adnexal metastases of an MPM. These results suggest that MPM should be considered in the differential diagnosis
of unexplained persistent high fever. Awareness of such atypical presentations of mesothelioma may help to make a correct
diagnosis. |
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| Keywords: | Malignant peritoneal mesothelioma High fever Metastasis |
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