Serum lipids, lipoproteins and sex-hormone binding globulin in breast cancer |
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| Authors: | A Ray S L Dayalu Naik A K Bahadur S T Pasha R S Rautela B K Sharma |
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| Institution: | (1) Institute of Cytology and Preventive Oncology (ICMR), Maulana Azad Medical College, 110002 New Delhi;(2) Department of Radiotherapy, Maulana Azad Medical College, 110002 New Delhi;(3) Division of Biochemistry and Biotechnology, National Institute of Communicable Diseases, 110054 Delhi |
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| Abstract: | Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein
(HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically
proven cases of breast cancer along with 146 control women. The mean levels of serum triglycerides, total cholesterol and
LDL-cholesterol were found to be significantly higher in breast cancer cases as compared to controls. However, lower mean
levels of serum HDL-cholesterol and sex-hormone binding glubulin (SHBG) were observed in breast cancer patients than the control
subjects. The results indicate a probable relation between serum lipids and the activity of sex-hormones. Moreover, the study
reflects an overall disturbance of lipid metabolism in the pathological process of breast cancer. |
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| Keywords: | Serum lipids related proteins and female breast cancer |
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