| 知母抗真菌有效成分的遗传致畸实验研究 |
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| 引用本文： | 李坊贞,刘建新,马廉兰,刘菲予.知母抗真菌有效成分的遗传致畸实验研究[J].赣南师范学院学报,2007,28(3):76-78. |
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| 作者姓名： | 李坊贞 刘建新 马廉兰 刘菲予 |
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| 作者单位： | 1. 赣南师范学院,化学与生命科学学院
2. 赣南医学院,江西,赣州,341000 |
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| 基金项目： | 赣南师范学院校科研和教改项目 |
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| 摘 要： | 采用小鼠急性毒性实验、小鼠股骨骨髓微核实验和精子畸变试验进行观察,对知母有效成分进行遗传毒理性实验.结果表明:在本实验条件下,知母抗真菌有效成分不存在急性毒性和遗传致畸性.
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| 关 键 词： | 知母抗真菌有效成分 急性毒性实验 微核实验 精子畸变 |
| 文章编号： | 1004-8332（2007）03-0076-03 |
| 收稿时间： | 2007-06-06 |
| 修稿时间： | 2007-06-06 |
The Reserch of the Teratogenic Genetic Experiments for Rhizoma Anemarrhenae's efficacious part in antifungal drugs |
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| LI Fang-zheng,LIU Jian-xing,MA Lian-rang,LIU Fei-yu.The Reserch of the Teratogenic Genetic Experiments for Rhizoma Anemarrhenae''''s efficacious part in antifungal drugs[J].Journal of Gannan Teachers' College(Social Science(2)),2007,28(3):76-78. |
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| Authors: | LI Fang-zheng LIU Jian-xing MA Lian-rang LIU Fei-yu |
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| Institution: | 1. School of Chemistry and Life Science , Gannan Normal University;2. Gannan Medical College, Ganzhou 341000,China |
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| Abstract: | Based on the observations of acute toxicity test and bone marrow micronucleus test for mice along with sperm aberration test,genetic toxicology test for effective components of Rhizoma Anemarrhenae was carried out.It is found that under the chosen test conditions,the antifungal constituents of Rhizoma Anemarrhenae show no acute toxicity and genetic teratogenicity. |
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| Keywords: | Rhizoma Anemarrhenae's efficacious part in antifungal drugs Acute Toxicity Test Micronucleus Test Sperm deformity Sperm abnormality |
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