Digitally simulated laboratory assessments (DSLAs) may be used to measure competencies such as problem solving and scientific inquiry because they provide an environment that allows the process of learning to be captured. These assessments provide many benefits that are superior to traditional hands-on laboratory tasks; as such, it is important to investigate different ways to maximize the potential of DSLAs in increasing student learning. This study investigated two enhancements—a pre-laboratory activity (PLA) and a learning error intervention (LEI)—that are hypothesized to enhance the use of DSLAs as an educational tool. The results indicate students who were administered the PLA reported statistically lower levels of test anxiety when compared to their peers who did not receive the activity. Furthermore, students who received the LEI scored statistically higher scores on the more difficult problems administered during and after the DSLA. These findings provide preliminary evidence that both a PLA and LEI may be beneficial in improving students’ performance on a DSLA. Understanding the benefits of these enhancements may help educators better utilize DSLAs in the classroom to improve student science achievement.