| 三七皂甙对小鼠空间学习记忆的影响 |
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| 引用本文： | 张楠楠,李亚,李世昌.三七皂甙对小鼠空间学习记忆的影响[J].福建体育科技,2008,27(5):41-43. |
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| 作者姓名： | 张楠楠 李亚 李世昌 |
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| 作者单位： | 1. 华东师范大学体育与健康学院,上海,200241
2. 曲阜师范大学生命科学学院,山东,曲阜,273165 |
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| 摘 要： | 本实验研究三皂甙（Rgl）对小鼠空间学习记忆的影响。将小白鼠随机分成四组，对照组灌胃0.5％CMC，给药组按剂量由低到高灌胃Rg130，60，90mg／kg，采用Y迷宫法检测小鼠的空间学习记忆能力。结果发现，给药组Rg160，90mg／kg小白鼠的Y迷宫实验正确反应次数与对照组相比有显著性差异（P〈0．05）；学习记忆力增强。说明三七皂苷能够改善小鼠空间学习记忆能力。
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| 关 键 词： | 三七皂甙 小鼠 Y迷宫法 空间学习记忆 |
Effect of Panax Notoginseng on Spatial Learning and Memory of mice in Y-maze Tasks |
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| Institution: | Zhang Nan-nan et al (1.College of Physical Education and Health, East China Normal University, Shanghai, 200241, China;2.College of Life Science, Qufu Normal University, Qufu Shandong, 273165, China) |
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| Abstract: | To investigate the effects of Panax notoginseng on Spatial learning and memory in mice.Methods:Kunming mice wrer randomly divided into four groups.Control group mice wrer daily administrated 0.5%CMC(p.o) for 7 days.The rest three gruops were daily administrated Rg1 30,60,90mg/kg(p.0) for 7 days,respectively.Y-maze was used to test the ability of spatial learning-memory in mice.Results:The number of correct reaction of treated mice by Rg1 60,90mg/kg in Y-maze showed a significant increase(P<0.05),compared with the control group mice(0.5%CMC),Conclusion:Rg1 effectively improved the ability of spatial learning-memory in mice. |
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| Keywords: | Saponins of Panax Notogingseng Mice Y-maze Spatial Learning and Memory |
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