| 香菇多糖及有氧运动对训练大鼠免疫系统影响的实验研究 |
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| 引用本文： | 陈美琴,华晔.香菇多糖及有氧运动对训练大鼠免疫系统影响的实验研究[J].浙江体育科学,2012(5):113-116. |
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| 作者姓名： | 陈美琴 华晔 |
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| 作者单位： | 江苏科技大学体育学院;江苏大学附属医院 |
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| 摘 要： | 目的:探讨香菇多糖和有氧运动对一次力竭运动大鼠免疫系统的影响,为改善力竭运动引起的免疫功能低下寻找有效的干预措施。方法:大鼠经过4周的香菇多糖灌药和有氧运动训练后,记录力竭运动时间,测试大鼠力竭后脾脏SOD,CAT,GSH-Px,MDA,AOC,用流式细胞术测大鼠外周血T细胞亚群的变化。结果:香菇多糖和有氧运动均可延长力竭时间(P<0.05),显著改善力竭大鼠脾脏CAT、MDA等抗氧化酶活性。一次力竭后大鼠CD3+T、CD4+T百分率和CD4+/CD8+比例非常显著降低(P<0.01),香菇多糖和有氧运动可有效预防T淋巴细胞亚群的这种变化。结论:香菇多糖和有氧运动均可提高大鼠运动能力,减轻力竭训练引起的免疫器官脂质过氧化损伤,改善运动疲劳,预防运动性免疫功能低下,且两者配合有协同作用。
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| 关 键 词： | 香菇多糖 有氧运动 免疫系统 |
Effect of Lentinan and Aerobic Exercise on Immune System in the Endurance-trained Rat |
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| CHEN Mei-qin,HUA Ye.Effect of Lentinan and Aerobic Exercise on Immune System in the Endurance-trained Rat[J].Zhejiang Sport Science,2012(5):113-116. |
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| Authors: | CHEN Mei-qin HUA Ye |
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| Institution: | 1.Physical Education College,Jiangsu Science and Technology University,Zhenjiang 212003,China; 2.The Affiliated Hospital of JiangSu University,ZhenJiang 212001,China) |
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| Abstract: | Objective:In order to search potent intervening means for low-level exercise-associated cellular immune capacities,effect of Lentinan and Aerobic exercise on on immune system in endurance-trained rats was observed.Methods: After 4 weeks test of Lentinan given and Aerobic Exercise to mice,time of exhaustive exercise were record,tests SOD,CAT,GSH-Px,MDA,AOC of spleen,percentage of peripheral T Lymphocyte subsets in circulating blood were tested by FCM.Results :Lentinan and Aerobic exercise could prolonged the exhausting exercise time(P < 0.05),improved Antioxidant enzymes activity such as CAT、MDA.Afer exhausting exercise,percentage of CD3+、CD4+and the ratio of CD4+ to CD8+ in Lymphocyte subsets,as well as were lower(P < 0.01).The change was prevented by Lentinan and aerobic exercise.Conclusion: Lentinan and aerobic exercise may improve exercise capacity,reduce lipid peroxidetion in immune organs caused by the exhaustive training,improve motion fatigue,and preven immunosuppression after exercise in rats,enhance effect after combinating the two means. |
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| Keywords: | mushroom polysaccharide aerobic exercise immune system |
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