| 缝隙连接蛋白在心肌疾病时的重构及其与运动性心律失常的关系 |
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| 引用本文： | 顾长海.缝隙连接蛋白在心肌疾病时的重构及其与运动性心律失常的关系[J].天津体育学院学报,2009,24(6):518-521. |
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| 作者姓名： | 顾长海 |
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| 作者单位： | 南阳理工学院体育教学部,南阳,473004 |
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| 摘 要： | 采用回顾性研究和前瞻性分析相结合的研究方法,综述连接蛋白(Connexins.cxs)的生物学功能及其在不同类型心肌疾病下的变化规律.Cxs在肥厚性心肌病、心肌缺血,左室压力超负荷等心肌疾病时发生重构,力竭运动和大强度运动下诱导的心脏病理改变类似于心肌疾病状态,且运动实践证明力竭运动和大强度运动造成Cxs分布模式改变和表达降低,推测大强度、高负荷运动诱导的心律失常可能与运动诱导心脏Cxs改变有关.
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| 关 键 词： | 连接蛋白 心肌肥大 心肌缺血 左室压力超负荷 运动训练 心律失常 |
| 收稿时间： | 9/3/2009 12:00:00 AM |
Connexins Reconstitution Under Cardiomyopathies and its Relation with Training-induced Arhythmia |
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| Gu Changhai.Connexins Reconstitution Under Cardiomyopathies and its Relation with Training-induced Arhythmia[J].Journal of Tianjin Institute of Physical Education,2009,24(6):518-521. |
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| Authors: | Gu Changhai |
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| Institution: | Dept. of PE, Nanyang Institute of Technology, Nanyang 473004, China |
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| Abstract: | Through using the combining method of retrospective research and prospective analysis, the author summarized the biological function and changes pattern in cardiac pathologic situations of (Connexins, Cxs). The Cxs reconstitution under the situations of hypertrophic cardiomyopathy, myocardial ischemic, overload of left ventricle pressure, moreover, exhausted training and high intensity training leading to distribution pattern derangement and downregulation
of Cxs. We presume that training-induced arhythmia may probably correlate with the changes of Cxs induced by overload and exhausted training. |
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| Keywords: | connexins myocardial hypertrophy myocardial ischemic overload of left ventricle pressure exercise training arrhythmia |
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