Motilin levels and electrogastroenterogram studies in hypothyroidism |
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| Authors: | Wang Hang-yong Cao Qian Li You-ming |
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| Institution: | (1) First Affiliated Hospital, College of Medicine, Zhejiang University, 310003 Hangzhou, China;(2) Sir Run Run Shaw Hospital, Medical College, Zhejiang University, 310016 Hangzhou, China |
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| Abstract: | To study the relationship between gastrointestinal dysfunction and motilin in patients with hypothyroidism. The plasma motilin
concentration was measured by radiommunoassay (RIA) in 30 patients with hypothyroidism and also in 30 controls. At the same
time, the electrogastroenterogram was also taken. Among the hypothyroidism patients, 56.6% had decreased gastric motility,
especially in gastric body and greater gastric curvature; 86.6% had decreased colonic motility, especially in the left half
of the colon. There were no significant differences of plasma motilin concentration between patients with hypothyroidism and
controls (P>0.05). There were also no differences between pre-treatment and post-treatment individuals, but significant differences were
observed in the electrogastroenterogram. We conclude that the plasma motilin concertration in hypothyroidism patients was
the same as that in normal patients, and that electrogastroenterogram studies in patients with gastrointestinal dysfunction
may be valuable. |
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| Keywords: | hypothyroidism motilin electrogastroenterogram |
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