Altered pattern of lipids in plasma and erythrocyte membranes of rheumatoid arthritis patients |
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| Authors: | D Vijayakumar K Suresh S Manoharan |
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| Institution: | (1) Department of Biochemistry, Faculty of Science, Annamalai University, 608 002 Annamalai Nagar, Tamilnadu, India |
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| Abstract: | The present study has investigated the levels of lipids, lipoprotein cholesterol (HDL and LDL cholesterol), thiobarbituric
acid reactive substances (TBARS) and vitamin E in plasma and erythrocyte membranes of twenty two clinically diagnosed adult
rheumatoid arthritis patients and an equal number of age matched healthy subjects. The levels of lipids and lipoprotein cholesterol
were markedly reduced in patients with rheumatoid arthritis as compared to healthy subjects. The altered lipid pattern may
be related to decreased lipoprotein cholesterol, fatty acids and impairment in antioxidant defence mechanism. |
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| Keywords: | Lipids Lipoproteins Rheumatoid arthritis |
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