| 几丁质对肿瘤及免疫作用的实验研究 |
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| 引用本文： | 房国坚,边敏章.几丁质对肿瘤及免疫作用的实验研究[J].科技通报,1996,12(4):233-235. |
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| 作者姓名： | 房国坚 边敏章 |
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| 作者单位： | 浙江省医学科学院 |
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| 摘 要： | 采用微晶几丁质，观察其对小鼠肿瘤的抑制作用及对免疫功能和细胞毒性的影响。结果显示：经灌胃途径给予剂量为４００ｍｇ／ｋｇ的几丁质制剂，具有延缓小鼠腹水瘤生和作用；对小鼠实体瘤Ｓ１８０生长具有抑制作用，其抑瘤率达３３％。研究还表明，几丁质对小鼠腹腔巨噬细胞的吞噬功能具有明显的促进作用；对人二倍体２ＢＳ细胞和小鼠骨髓瘤ＳＰ２／０细胞地直接
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| 关 键 词： | 几丁质 腹水瘤 免疫作用 癌 抑制作用 |
Preliminary Studies on Antitumor Activities and Immune Function of Chitin |
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| Fang Guojian, Bian Minzhang.Preliminary Studies on Antitumor Activities and Immune Function of Chitin[J].Bulletin of Science and Technology,1996,12(4):233-235. |
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| Authors: | Fang Guojian Bian Minzhang |
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| Institution: | Zhejing Academy of Medical Sciences .Hangzhou 310013 |
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| Abstract: | The growth of mice ascites carcinoma and solid tumor S180 was significantly suppressed when chitin was administrated orally at the dosage of 400mg/kg. the inhibition rate of 5180 was 33%. It was also found that chitin increased the phagocytic function of mice peritoneal macropbage significantly, and had no direct cytotoxic effect on human diploid cells 2BS and mice myeloma SP2/0. |
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| Keywords: | chitin ascites tumor solid tumor S180 macrophagus Immune function |
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