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制何首乌致小鼠网状内皮系统对血流中惰性炭粒的吞噬廓清能力的影响
引用本文:韩宁娟,王莉,方欢乐,牛睿.制何首乌致小鼠网状内皮系统对血流中惰性炭粒的吞噬廓清能力的影响[J].杨凌职业技术学院学报,2013(3):16-17.
作者姓名:韩宁娟  王莉  方欢乐  牛睿
作者单位:1. 西安培华学院,陕西西安,710065
2. 陕西省彬县动物卫生监督所,陕西彬县,713500
摘    要:目的:研究不同浓度的制何首乌水煎浓缩液致小鼠网状内皮系统对血流中惰性炭粒的吞噬廓清能力的影响,探讨制何首乌调整免疫的最佳浓度。方法:以小鼠为实验对象,用2g/mL(大剂量)、1g/mL(中剂量)、0.5g/mL(小剂量)三种不同浓度的制何首乌水煎液给小鼠灌胃12d,采用炭粒廓清法来检测RES吞噬异物的能力。结果:大剂量能明显增强RES吞噬功能,中、小剂量组无显著性差异。结论:制何首乌浓度为2g/ml时可显著提高实验小鼠非特异性免疫功能,具有扶正固本的作用。

关 键 词:廓清  网状内皮系统  制何首乌  吞噬

Effect of Prepared Radix Polygoni Multiflori on Phagocytic Clearance Ability of Inert Carbon
HAN Ningjuan , WANG Li , FANG Huanle , NIU Rui.Effect of Prepared Radix Polygoni Multiflori on Phagocytic Clearance Ability of Inert Carbon[J].Journal of Yangling Vocational & Technical College,2013(3):16-17.
Authors:HAN Ningjuan  WANG Li  FANG Huanle  NIU Rui
Institution:HAN Ning-juan;WANG Li;FANG Huan-le;NIU Rui(Xi'an Peihua University;Binxian Animal Health Inspection Institute; )
Abstract:The paper studied the effect of prepared Radix Polygoni Multiflori decoction concentrated at different concentration on the phagocytic clearance ability of mice to inert carbon particles flow,exploring the best concentration of prepared Radix Polygoni Multiflori adjusting immunity.The mouse was taken as the experimental object,using 2g/ml(high dose),1g/ml(middle dose),0.5g/ml(low dose)of three kinds of prepared Radix Polygoni Multiflori decoction of different concentrations of mice for 12days,using carbon particle clearance method to detect RES swallowed foreign bodies.The result shows that the high dose group can increase the phagocytic function of RES,no significant difference in small-and middle dose group.Prepared Radix Polygoni Multiflori(concentration 2g/ml)can significantly improve the non-specific immune function in mice,with Fuzheng equity role.
Keywords:clearance  prepared Radix Polygoni Multiflori  RES  Phagocytosis
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