| 三元能量提高妥布拉霉素产生菌产抗能力的研究 |
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| 引用本文： | 顾觉奋,王鲁燕,陈正尧.三元能量提高妥布拉霉素产生菌产抗能力的研究[J].人天科学研究,1996(3). |
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| 作者姓名： | 顾觉奋 王鲁燕 陈正尧 |
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| 作者单位： | 中国药科大学抗生素研究室，中国药科大学抗生素研究室，中国元极学研究会科技应用委员会 南京，210009，南京，210009，鄂州，436000 |
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| 基金项目： | 江苏省自然科学基金，中国元极学研究会科研基金 |
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| 摘 要： | 通过平行实验,考察了三元能量处理后的妥布拉霉素(TOB)诱变高产株在不同组合培养基中的发酵水平及主组份含量,实验结果表明:5株三元能量处理后的高产菌在A、B、C 配方培养基中,以C配方培养基为最适,从而使发酵单位提高了 85.12％,主组份含量由 41.35％提高到 56.08％。
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| 关 键 词： | 三元能量诱变株 妥布拉霉素(TOB) 产抗能力 |
A Study of the Influence of Three-yuan Energy upon the Improvement of the Antibiosis Generativity of Tobramycin-Cultured Fungi |
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| Authors: | Wang Luyan Chen Zhengyao Gu Juefen female prof Division of Antibiotics Pharmaceutical University of China Nanjing PRC |
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| Institution: | Wang Luyan Chen Zhengyao Gu Juefen,female,prof. , Division of Antibiotics,Pharmaceutical University of China,Nanjing,210009,PRC. |
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| Abstract: | An examination is conducted of the fermentativity and the principal constituent content of the tobramycin-mutagenic high-yield fungi after the treatment of Three-yuan energy in different substrata of different compositions, by parallel experiment, whose results show that high-yield fungi after the treatment of three yuan energy,among the substrata of A,B and C formulae,develop best in C so that the fermentation units increase by 82.12% and the content of the principal constituent increases from 41. 35% to 56.08%. |
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| Keywords: | Three-yuan energy mutagenic fungi tobramycin (TOB) antibios is generativity |
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