Efficacy of a Fish Protein Hydrolysate in Malnourished Children |
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| Authors: | Knut Olav Nesse A P Nagalakshmi P Marimuthu Mamta Singh |
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| Institution: | (1) Zymtech Production AS, Lesja, Norway;(2) Consortium Clinical Research Pvt. Ltd, Tamil Nadu, India;(3) Department of Biostatistics, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India;(4) Jamia Milia Islamia, New Delhi, India;(5) Plant Pathology Division, Indian Agricultural Research Institute, Pusa Campus, C/O Dr. P. Usha Sarma, Room no. 17, New Delhi, 110012, India; |
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| Abstract: | Protein hydrolysates are good nutritional supplements as their bioactive ingredients can be easily absorbed and utilized for
various metabolic activities. A fish protein hydrolysate (Amizate), prepared by a unique process of hydrolysis has the advantage
of high di/tri peptide content (<10 kDa) along with essential and non essential amino acids, micronutrients and vitamins.
The effect of Amizate on malnourished children (6–8 years, a total of 438) of Grade I and II (Gomez’s classification) with
respect to immunoglobulins, CD4/CD8 ratios and hemoglobin was examined. Measurement of these parameters during the user trial
study (at the beginning and the end after 4 months) indicated that the levels of the immunological parameters were not significantly
altered by the Amizate treatment. The values of immunoglobulins and CD4/CD8 ratios of malnourished children (India) are in
the normal range and are in accordance with the reported values of various ethnic groups. |
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| Keywords: | Protein hydrolysates Immunoglobulin Malnourishment Nutrition |
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