Thymus |
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| Authors: | Shamik Majumdar Sanmoy Pathak Dipankar Nandi |
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| Institution: | 1.Department of Biochemistry Indian,Institute of Science,Bengaluru,India |
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| Abstract: | The immune system protects our bodies against infections and cancers. This review introduce readers to the thymus – a primary lymphoid organ – which is the site of development and maturation of functional T lymphocytes. Progenitor stem cells arise from the bone marrow and undergo sequential development in the thymus where non-self-reactive T cells are selected. Subsequently, post selection and maturation, the mature T cells exit the thymus as naïve T cells into the peripheral lymph nodes. Studies on the thymus are likely to enhance our understanding of T cell development and reduce disease burdens by improving the cellular immune response. |
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