| 甲磺酸双氢麦角毒碱片含量均匀度测定方法学研究 |
| |
| 引用本文： | 牟微,常明,任蕾,王婧,熊婷,余云霓.甲磺酸双氢麦角毒碱片含量均匀度测定方法学研究[J].石家庄学院学报,2011,13(3):33-35. |
| |
| 作者姓名： | 牟微 常明 任蕾 王婧 熊婷 余云霓 |
| |
| 作者单位： | 石家庄学院化工学院,河北石家庄,050035 |
| |
| 基金项目： | 石家庄市科学技术研究与发展指导计划 |
| |
| 摘 要： | 建立甲磺酸双氢麦角毒碱片的含量均匀度测定方法.采用对二甲氨基苯甲醛作为显色剂与甲磺酸双氢麦角毒碱显色,以580 nm为测定波长,采用紫外分光光度法进行测定.本方法测定的线性范围47.79～77.66 mg/L(r=0.999 9),平均回收率(n=9)为100.9%.本法简便、快速、准确,可较好评价甲磺酸双氢麦角毒碱片的含量均匀度,为其质量控制提供依据.
|
| 关 键 词： | 双氢麦角毒碱 片剂 分光光度法 含量均匀度 |
Research on the Content Uniformity of Co-dergocrine Mesylate Tablets |
| |
| MU Wei,CHANG Ming,REN Lei,WANG Jing,XIONG Ting,YU Yun-ni.Research on the Content Uniformity of Co-dergocrine Mesylate Tablets[J].Journal of Shijiazhuang University,2011,13(3):33-35. |
| |
| Authors: | MU Wei CHANG Ming REN Lei WANG Jing XIONG Ting YU Yun-ni |
| |
| Institution: | MU Wei,CHANG Ming,REN Lei,WANG Jing,XIONG Ting,YU Yun-ni(School of Chemical Technology,Shijiazhuang University,Shijiazhuang,Hebei 050035,China) |
| |
| Abstract: | A Ultra Violet-Visible Spectrophotometry method for determining content uniformity of co-dergocrine mesilate is established.As a chromogenic agent,4-dimethylaminobenzaldehyde is adopted to co-dergocrine mesilate.The maximum absorption is 580 nm.The results show that the linear relationship of the peak and concentration is determined as 47.79~77.6 mg/L with a regression coefficient of 0.999 9,and the average recovery rate(n=9) is 100.9%.The method is convenient,fast and accurate.It can be applied to approve ... |
| |
| Keywords: | co-dergocrine mesilate tablet Violet-Visible Spectrophotometry content uniformity |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
