Role of Vitamin D Supplementation in Hypertension |
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| Authors: | R K Goel Harbans Lal |
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| Institution: | (1) Departments of Medicine and Biochemistry, Maharaja Agrasen Medical College, Hisar, Agroha, 125047, Haryana, India; |
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| Abstract: | Role of Vitamin D supplementation was studied in patients with hypertension. One hundred hypertensive patients (group I) were
given conventional antihypertensive drugs while another 100 patients (group II), in addition, were supplemented with Vitamin
D3 (33,000 IU, after every 2 weeks, for 3 months). Besides diastolic and systolic blood pressure, serum calcium, phosphorous,
alkaline phosphatase, albumin, albumin-corrected calcium, and 24 h urinary creatinine levels were estimated in both the groups
before the start of treatment and after 3 months. Vitamin D supplementation showed a more significant decrease in systolic
blood pressure. This group also showed a significant increase in serum calcium as well as albumin-corrected calcium with a
decrease in phosphorous. Results of the study confirm that Vitamin D supplementation has a role in reducing blood pressure
in hypertensive patients and that it should be supplemented with the antihypertensive drugs. More extensive studies with a
larger group, to draw a definite conclusion, are in progress. |
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| Keywords: | Vitamin D supplementation Hypertension Blood pressure |
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