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Manipulating particle trajectories with phase-control in surface acoustic wave microfluidics
Authors:Orloff Nathan D  Dennis Jaclyn R  Cecchini Marco  Schonbrun Ethan  Rocas Eduard  Wang Yu  Novotny David  Simmonds Raymond W  Moreland John  Takeuchi Ichiro  Booth James C
Abstract:We present a 91?MHz surface acoustic wave resonator with integrated microfluidics that includes a flow focus, an expansion region, and a binning region in order to manipulate particle trajectories. We demonstrate the ability to change the position of the acoustic nodes by varying the electronic phase of one of the transducers relative to the other in a pseudo-static manner. The measurements were performed at room temperature with 3?μm diameter latex beads dispersed in a water-based solution. We demonstrate the dependence of nodal position on pseudo-static phase and show simultaneous control of 9 bead streams with spatial control of ?0.058?μm/deg?±?0.001?μm/deg. As a consequence of changing the position of bead streams perpendicular to their flow direction, we also show that the integrated acoustic-microfluidic device can be used to change the trajectory of a bead stream towards a selected bin with an angular control of 0.008?deg/deg?±?0.000(2) deg/deg.
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