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米非司酮25mg用于紧急避孕156例观察
引用本文:刘晨,宋宝君,张少萍,王桂荣,孙临河.米非司酮25mg用于紧急避孕156例观察[J].河北北方学院学报(医学版),2001(1).
作者姓名:刘晨  宋宝君  张少萍  王桂荣  孙临河
作者单位:张家口医学院一附院妇产科,张家口医学院一附院妇产科,内蒙古自治区多伦县中医院,内蒙古自治区多伦县妇幼保健站,蔚县县医院 075000,075000,027300,027300
摘    要:目的:了解在无保护性交后72h内应用小剂量米非司酮紧急避孕的临床效果、副反应及对月经的影响。方法:将无保护性交后72h内的156例妇女给予单次口服25mg米非司酮,观察其避孕效率,用Dixon方法计算有效率。结果:1例因方法失败,156例妇女预期总妊娠数为10.188例,实际妊娠数为1例,避孕有效率为90.18%,服药后出血发生率为10.3%,与上海协作组比较P>0.05。结论用25mg米非司酮作为紧急避孕无严重副反应,对月经周期无明显于扰。

关 键 词:米非司酮  紧急避孕

Clinical Analysis on the effect of 25mg Mifepristone in Emergency Contraception
Liu Chen,SongBaojun,Wang Guirong,et al.Clinical Analysis on the effect of 25mg Mifepristone in Emergency Contraception[J].Journal of Hebei North University:Medical Edition,2001(1).
Authors:Liu Chen  SongBaojun  Wang Guirong  
Institution:Liu Chen,SongBaojun,Wang Guirong,et al Department of Gynecology,the First Affiliated Hospital of Zhangjiakou Medical GDllegc,075000
Abstract:Objective: To investigate the effectiveness and side-effects of low doses of mifepristone given orally within 72 hours after unprotected intercourse as an emergency contreceptive and on menstrual pattern. Methods: 156 cases healthy women were given 25mg mifepristone orally within 72 hours after unprotected intercourse. The efficacy rates of contraception were estimated according to Dixon method. Results: The total expected number of pregnancy was 10. 188 in 156 subjects enrolled in the study. The number of observed pregnancy resulted from method failure was 1 case. The contraceptive effectiveness rate was 90. 18%. The incidences of withdrawal bleeding were 10.3% . Conclusion: Single oral administration of 25mg mifepristone was safe and effective regimen for emergency contraception with no serious side - effects and no obvious disturbance on menstrual pattern.
Keywords:Mifepristonc  Emergency contraception
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