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Serum adenosine deaminase in carcinoma breast
Authors:Ajay Kumar Khanna  Sujit Yadav  Z Ali  N C Arya  Anuradha Khanna
Institution:1. Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, 221 005, Varanasi, India
2. Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, 221 005, Varanasi, India
3. Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, 221 005, Varanasi, India
4. Department of Gynecology, Institute of Medical Sciences, Banaras Hindu University, 221 005, Varanasi, India
Abstract:Serum Adenosine Deaminase (ADA) activity was studied in 20 control cases and 32 patients with carcinoma breast. In control group the ADA activity ranged from 13–94 IU/L with a mean of 43.75±21.55 IU/L while in patients of carcinoma breast it was 16–95 IU/L with a mean of 47.46±22.54 IU/L, but these values were not statistically different. The ADA activity was also compared with other parameters in patients of carcinoma breast but the difference was not statistically significant in the various parameters like duration of disease, menopausal status, tumor size, hemoglobin level, total leucocyte count, absolute lymphocyte count, total serum proteins, serum albumin, histological grade of tumor and lymphocytic infiltration. The only significant difference in ADA activity was when N1 status of lymph node was compared with N2 status of lymph node.
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