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Effect ofPremna latifolia Roxb andImperata arundinacea Cyril onin vitro oxalate crystal growth
Authors:C Aravindakshan  N Jayanthi Bai
Institution:1. Department of Biochemistry, Medical College, 695 011, Trivandrum
Abstract:Two indigenous drugsPremna latifolia Roxb (Agnimandha) andImperata arundinacea Cyril (Darbha) were studied for their anticalculogenic effect at 20 and 100 mg concentrations. Both the concentrations were found to be equally effective in reducing the size of oxalate crystal growthin vitro over a period of 30 days. There was no change in infra red spectra while scanning electron microscope analysis showed development of cracks in the interior of the crystals and a tendency for rupture of crystals. Chemolysis appears to be the mechanism of action of the drugs.
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