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| C-erbB-2基因蛋白在三种癌瘤组织中表达的分析 | |
| 引用本文： | 薄爱华,王金科,李洪涛,杨晓明,白丽娜.C-erbB-2基因蛋白在三种癌瘤组织中表达的分析[J].河北北方学院学报(医学版),2002,19(5):1-3. |
| 作者姓名： | 薄爱华 王金科 李洪涛 杨晓明 白丽娜 |
| 作者单位： | 1. 张家口医学院电镜室,075000 2. 石家庄白求恩军医学院,050000 3. 张家口沈家屯医院,075000 |
| 摘 要： | 目的 :为探讨C -erbB - 2蛋白在胃癌、大肠癌和乳腺癌中表达的异同和意义。方法 :取胃癌 114例、大肠癌 10 4例和乳腺癌 10 6例 ,石蜡切片 ,SP免疫组织化学染色。结果 :C-erbB - 2在胃癌、大肠癌和乳腺癌中的阳性率分别为 71.9%、5 7.7%和 5 4 .7%。C -erbB - 2在胃癌和大肠癌中的表达与患者年龄有关 ;C -erbB - 2表达与大肠癌分化程度及乳癌恶性程度有关。结论 :C -erbB - 2高表达是大肠癌、乳癌恶性度高 ,预后不良的指标 |
| 关 键 词： | 胃癌 大肠癌 乳腺癌 免疫组织化学 |
| 文章编号： | 1005-8796(2002)05-01-03 |
Study on expression C - erbB - 2 Gene in Three Different types |
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| Bo Aihua,Wang Jinke,Li Hongtao,et al Zhangjiakou Medical College,Zhangjiakou,China.Study on expression C - erbB - 2 Gene in Three Different types[J].Journal of Hebei North University:Medical Edition,2002,19(5):1-3. | |
| Authors: | Bo Aihua Wang Jinke Li Hongtao Zhangjiakou Medical College Zhangjiakou China |
| Institution: | Bo Aihua,Wang Jinke,Li Hongtao,et al Zhangjiakou Medical College,Zhangjiakou,075000,China |
| Abstract: | Objective: To study the expression and the significance of C-erbB-2 in different types in gastric carcinoma colorectal carcinoma and breast carcinoma. Method: The 114 cases of gastric carcinoma 104 colorectal carcinoma and 106 breast carcinoma are collected , then sections are parafined and Sp immulnohischenistry is used. Result: Positive rates of C-erbB-2 in gastric ?colorectal ard breast carcinoma are 71.9% , 57.7% and 54.7% respectively . The expression of C- erbB- 2 in gastric and colorectal carcinoma is correlative with the age of the paients , with differentiation in colorectal carcinoma and malignacy in breast carcinoma as well. Conclusion: The high-expression of C-erbB-2 in colorectal and breast carcinoma is the index which indicates high malignacy and bad progress. |
| Keywords: | gastric carcinoma colorectal carcinoma breast carcinoma immulnohistochimistry |
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