金樱子多糖体外抗脂质过氧化和红细胞溶血作用研究 |
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引用本文: | 皮建辉,胡朝暾,郑晴,蔡婧.金樱子多糖体外抗脂质过氧化和红细胞溶血作用研究[J].怀化师专学报,2012(5):11-15. |
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作者姓名: | 皮建辉 胡朝暾 郑晴 蔡婧 |
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作者单位: | [1]怀化学院.民族药用植物资源研究与利用湖南省重点实验室 [2]湘西药用植物与民族植物学湖南省高校重点实验室 [3]生命科学系,湖南怀化418008 |
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基金项目: | 民族药用植物资源研究与利用湖南省重点实验室委托项目(HHUW2010-71). |
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摘 要: | 采用体外实验研究了金樱子多糖(RP)对小鼠肝脏自发性脂质过氧化、H2O2诱导的脂质过氧化、Fe^2+-Vc诱导的肝线粒体氧化损伤和H2O2诱导的红细胞氧化溶血的影响,比较了金樱子多糖和维生素C(Vc)的抗脂质过氧化作用.结果表明:金樱子多糖具有较强的体外抗脂质过氧化作用,且呈现良好的量效关系;其抗氧化活性明显高于维生素C.
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关 键 词: | 金樱子多糖 脂质过氧化 红细胞溶血 抗氧化活性 |
Studies on the Effects of Polysaccharide from Rosa Lacvigata Michx in Anti- lipoperoxidant and Anti- erythrocyte Haemolysis in Vitro |
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Institution: | PI Jian - hui , HU Chao - tun , ZHENG Qing , CAI Jin ( 1. Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources ; 2. Laboratory of Hunan Higher Education for Hunan - western Medicinal Plant and Ethnobotany ; 3. Department of Life Science, Huaihua University, Huaihua , Hunan 418008 ) |
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Abstract: | In this paper, the effects of Rosa Lacvigata Polysaccharide (RP) in the spontaneous lipid peroxidation, the lipid peroxidation and erythrocyte haemolysis induced by H2O2 , and mitochondrial oxidative damage induced by Fe^2+ - Vc in mice liver were studied, in vitro. And the anti - lipoperoxidation of RP was compared to that of Vc. The results indicated that RP has strong vitro function on anti - lipoperoxidation, and there was obviously dose - effect relationship between activity and concentration. And the antioxidant activity of RP was obviously stronger than that of Vc. |
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Keywords: | Rosa Lacvigata polysaccharide lipid peroxidation erythrocytic hemolysis anti - oxidative activity |
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