| 开启中国设计育种新篇章——“分子模块设计育种创新体系”战略性先导科技专项进展 |
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| 引用本文： | 薛勇彪,种康,韩斌,桂建芳,王台,傅向东,何祖华,储成才,田志喜,程祝宽,林少扬.开启中国设计育种新篇章——“分子模块设计育种创新体系”战略性先导科技专项进展[J].中国科学院院刊,2015,30(3):393-402. |
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| 作者姓名： | 薛勇彪 种康 韩斌 桂建芳 王台 傅向东 何祖华 储成才 田志喜 程祝宽 林少扬 |
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| 作者单位： | 中国科学院遗传与发育生物学研究所 北京100101,中国科学院植物研究所 北京100093,中国科学院上海生命科学研究院 上海200031,中国科学院水生生物研究所 武汉430072,中国科学院植物研究所 北京100093,中国科学院遗传与发育生物学研究所 北京100101,中国科学院上海生命科学研究院 上海200031,中国科学院遗传与发育生物学研究所 北京100101,中国科学院遗传与发育生物学研究所 北京100101,中国科学院遗传与发育生物学研究所 北京100101,中国科学院遗传与发育生物学研究所 北京100101 |
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| 基金项目： | 中科院分子模块设计育种创新体系战略性先导科技专项(XDA08000000) |
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| 摘 要： | "分子模块设计育种创新体系"战略性先导科技专项以水稻为主,小麦、鲤等为辅,利用野生种、农家品种和主栽(养)优良品种等种质资源,综合运用基因组学、系统生物学、合成生物学等手段,解析高产、稳产、优质、高效等重要农艺(经济)性状的分子模块,揭示水稻复杂性状全基因组编码规律,发展多模块非线性耦合理论和"全基因组导航"分子模块设计育种技术,优化多模块组装的品种设计的最佳策略,建立从"分子模块"到"设计型品种"的现代生物技术育种创新体系,为实现全基因组水平多模块优化组装、培育新一代超级品种提供系统解决方案。文章介绍了该专项的背景、总体目标、研究内容、进展及发展展望。
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| 关 键 词： | 水稻 复杂性状 分子模块 分子模块设计育种 模块耦合与组装 育种技术升级换代 |
| 收稿时间： | 2015/4/10 0:00:00 |
New Chapter of Designer Breeding in China: Update on Strategic Program of Molecular Module-Based Designer Breeding Systems |
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| Xue Yongbiao,Zhong Kang,Han Bin,Gui Jianfang,Wang Tai,Fu Xiangdong,He Zuhu,Chu Chengcai,Tian Zhixi,Chen Zhukuan and Lin Shaoyang.New Chapter of Designer Breeding in China: Update on Strategic Program of Molecular Module-Based Designer Breeding Systems[J].Bulletin of the Chinese Academy of Sciences,2015,30(3):393-402. |
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| Authors: | Xue Yongbiao Zhong Kang Han Bin Gui Jianfang Wang Tai Fu Xiangdong He Zuhu Chu Chengcai Tian Zhixi Chen Zhukuan and Lin Shaoyang |
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| Institution: | Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China,Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China,Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China,Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China,Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China,Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China,Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China,Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China,Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China,Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China and Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China |
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| Abstract: | Sustained and stable productions of main agricultural products such as rice, wheat, and fish are essential to guarantee food security in China, which depends on innovations in breeding theories and technologies. Using genetic resources of rice as well as wheat and fish, and a combination of omics, systems biology, and synthetic biology, a strategic program named the Molecular Module-based Designer Breeding Systems was initiated in 2013 and aimed to (1) dissect molecular modules controlling complex traits including yield, stress tolerance, quality, and nutrient efficiency; (2) reveal the molecular mechanisms of complex trait formation at genome-scale, and the coupling mechanisms of diverse molecular modules, (3) develop the techniques for an optimized genome-wide multi-module assembly and an effective designer breeding scheme. Moreover, this project also aimied to establish a systematic solution for designing and breeding elite varieties. This program includes four projects: (1) mining and functional analysis of molecular modules controlling complex traits; (2) analysis of module systems and their coupling effects; (3) molecular design and breeding of elite varieties;and (4) construction of breeding bases and pipelines for designer breeding. Within the first five years of the program, it aims to obtain 16-20 molecular modules and 12-15 module systems applicable in designer breeding, 1-2 computational models used for evaluating the coupling effect of diverse modules, achieve an optimal coupling assembly of yield, quality, tolerance, and nutrient efficiency, and breed 10-15 designer varieties. So far, this program has dissected 20 modules from rice including 5 for high yield, 2 for resistance to rice blast and banded sclerotial blight, 3 for tolerance to cold, and 2 for nitrogen utilization efficiency. It has revealed several module systems controlling oil biosynthesis in soybean, and bred 14 designer rice varieties for field tests or regional trials. In addition, promising progresses have been achieved in establishing breeding bases and pipelines. The program is expected to make substantial contributions to upgrading both crop and animal breeding technologies. |
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| Keywords: | rice complex traits molecular module molecular module-based designer breedings module coupling and assembly breeding technology upgrading |
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