| 3,5-二羟基苯甲酰腙类化合物的合成及其生物活性 |
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| 引用本文： | 林彩萍,葛昌华,潘富友,王锦文,张利龙.3,5-二羟基苯甲酰腙类化合物的合成及其生物活性[J].台州学院学报,2006,28(6):59-61,64. |
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| 作者姓名： | 林彩萍 葛昌华 潘富友 王锦文 张利龙 |
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| 作者单位： | 1. 台州学院,医药化工学院,浙江,临海,317000;浙江工业大学,浙江,杭州,310000
2. 台州学院,医药化工学院,浙江,临海,317000 |
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| 摘 要： | 合成了未见文献报道的10个标题化合物,所有化合物通过紫外光谱,红外光谱,核磁共振氢谱和元素分析表征,确定了化合物的组成和结构,并测定了它们对金黄色葡萄球菌、绿脓杆菌、肺炎克雷伯氏菌和大肠杆菌的抑制作用。抑菌活性试验表明,部分目标化合物具有较好的抑菌活性。
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| 关 键 词： | 苯甲酰腙 合成 抑菌活性 |
| 文章编号： | 1672-3708（2006）06-0059-03 |
| 收稿时间： | 2006-09-09 |
| 修稿时间： | 2006-09-092006-09-25 |
Synthesis and Biological Activities of 3,5 - Dihydroxybenzoylhydrazide Compounds |
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| LIN Cai-ping,GE Chang-hua,PAN Fu-you,WANG Jin-wen,ZHANG Li-rong.Synthesis and Biological Activities of 3,5 - Dihydroxybenzoylhydrazide Compounds[J].Journal of Taizhou University,2006,28(6):59-61,64. |
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| Authors: | LIN Cai-ping GE Chang-hua PAN Fu-you WANG Jin-wen ZHANG Li-rong |
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| Institution: | 1. School of Life Science, Pharmaceutical and Chemical Engineering, Taizhou University, Linhai 317000, China; 2. Zhejiang University of Technology, Hangzhou 310000, China |
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| Abstract: | The novel Compounds of Di-3,5-Dihydroxybenzoylhydrazide have been synthesized in the yields of 68.3 % ~94.4 %. The structures of the compounds were confirmed by means of UV, IR, HNMR and elemental analysis. Antibacterial activities tests have shown that the parts of aim compounds have abroad and excellent activities. |
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| Keywords: | benzoylhydrazide Synthesis Antibacterial Activities |
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