| 运动对抑郁症的影响及干预研究 |
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| 引用本文： | 刘志刚.运动对抑郁症的影响及干预研究[J].四川体育科学,2014(3):43-47,56,69. |
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| 作者姓名： | 刘志刚 |
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| 作者单位： | 玉溪师范学院体育学院,云南玉溪653100 |
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| 摘 要： | 抑郁症不仅是大脑功能上的失调，抑郁患者突触间隙单胺类递质与其受体功能下降，海马体积明显缩小，还伴随着认知功能的下降。抗抑郁药物靠提高突触间隙5-HT的含量或增强其受体的功能发挥抗抑郁作用。而运动主要通过 VGF、内啡肽、VEGF、BDNF、IGF-1和5-TH来发挥抗抑郁作用。本文就抑郁症发病机制、药物及运动的抗抑郁作用进行阐述。
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| 关 键 词： | 抑郁症 运动 认知 VGF BDNF 5-TH |
Study on the Impact of Exercise Intervention on Depression |
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| LIU Zhi-gang.Study on the Impact of Exercise Intervention on Depression[J].Sichuan Sports Science,2014(3):43-47,56,69. |
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| Authors: | LIU Zhi-gang |
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| Institution: | LIU Zhi-gang (Yuxi Normal University, Yunan Yuxi, 653100, China.) |
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| Abstract: | Depression is not only a disease of brain function disorders, but also synaptic cleft monoamine neurotransmitters and its receptors function decline. Depressed patients hippocampal volume is significantly reduced, accompanied by a decline in cognitive function. Antidepressant drugs by increasing the content of 5-HT in synaptic gap or enhance the function of its receptor play antidepressant effect. Exercise mainly through VGF, endorphins, VEGF, BDNF, IGF-1 and 5-TH play an antidepressant effect. This article reviewed the pathogenesis of depression, antidepressant effects of drugs and exercise. |
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| Keywords: | Depression Exercise Cognitive VGF BDNF 5-TH |
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