| 运动干预对成人代谢综合征患者心血管危险因素影响的Meta分析 |
| |
| 引用本文： | 许瀚,尹毅,赵燕.运动干预对成人代谢综合征患者心血管危险因素影响的Meta分析[J].中国体育科技,2020(5):59-70. |
| |
| 作者姓名： | 许瀚 尹毅 赵燕 |
| |
| 作者单位： | 成都体育学院;成都第一骨科医院 |
| |
| 基金项目： | 四川省科技厅应用基础项目(2019YJ0524);成都体育学院运动医学与健康研究所创新课题(CX19B03);国家体育总局运动医学重点实验室暨运动医学四川省重点实验室基金(CTYY2017013)。 |
| |
| 摘 要： | 目的:通过Meta分析,评价运动对成人代谢综合征患者心血管危险因素的影响效果。方法:检索PubMed、EMBASE、The Cochrane Library、中国知网、万方、中国生物医学等数据库,严格按照纳入与排除标准选取文献,提取数据,进行质量评价,在Review Manager5.3软件上进行统计分析。结果:纳入文献共计10篇,包含15个RCT,合计476名患者。Meta分析结果显示,与对照组相比,有氧运动能够显著改善代谢综合征患者的腰围MD=-2.07(-3.24,-0.90)(P=0.005)、空腹血糖MD=-0.14(-0.26,-0.03)(P=0.02)、高密度脂蛋白胆固醇MD=2.03(0.12,3.94)(P=0.04)、甘油三酯MD=-17.60(-34.76,-0.44)(P=0.04)、总胆固醇MD=-9.38(-16.25,-2.51)(P=0.007)、收缩压MD=-7.18(-10.81,-3.55)(P=0.0001)、舒张压MD=-2.93(-4.48,-1.37)(P=0.0002)以及峰值耗氧量MD=2.44(0.91,3.98)(P=0.0002);而抗阻训练或抗阻结合低强度有氧运动仅对代谢综合征患者的收缩压MD=-8.81(-14.98,-2.63)(P=0.005)、体脂量MD=-3.06(-4.70,-1.42)(P=0.0002)有显著影响。有氧运动和抗阻训练或抗阻训练结合低强度有氧运动均未对体重及身体质量指数有显著作用。结论:有氧运动是成人代谢综合征患者改善其心血管危险因素的最佳运动模式,对腰围、空腹血糖、高密度脂蛋白胆固醇、甘油三酯、总胆固醇、收缩压、舒张压以及峰值耗氧量的改善均有显著优势,能有效降低心血管疾病的发病风险;而抗阻训练或抗阻训练结合低强度有氧运动只降低了收缩压和体脂量。
|
| 关 键 词： | 代谢综合征 心血管危险因素 有氧运动 抗阻训练 META分析 |
Meta-analysis of Exercise Effect on the Cardiovascular Risk Factors in Adults with Metabolic Syndrome |
| |
| XU Han,YIN Yi,ZHAO Yan.Meta-analysis of Exercise Effect on the Cardiovascular Risk Factors in Adults with Metabolic Syndrome[J].China Sport Science and Technology,2020(5):59-70. |
| |
| Authors: | XU Han YIN Yi ZHAO Yan |
| |
| Institution: | (ChengduSportUniversity,Chengdu 610041,China;No.1 Orthopedics Hospital of Chengdu,Chengdu 610031,China) |
| |
| Abstract: | Objective:To evaluate the effect of exercise intervention on cardiovascular risk factors in adults with Metabolic Syndrome(MS)by meta-analysis.Methods:Six electronic databases were searched,including PubMed,EMBASE,the Cochrane Library,China Knowledge Network,Wan fang,and China Biomedicine.Documents of Randomized Controlled Trial(RCT)investigating the effect of exercise on cardiovascular risk factors in adult MS patients were selected in accordance with the inclusion and exclusion criteria.The methodological qualities of included studies were evaluated using Cochrane analysis.All the data of cardiovascular risk factors was meta-analyzed in a random and fixed-effect model with Review Manager 5.3 software.Results:10 articles were included involving 476 patients and 15 RCTs.Meta-analysis showed that compared with the control group,aerobic exercise significantly improved the cardiovascular risk factors of patients with MS including waist circumference(WC)MD=-2.07(-3.24,-0.90)(P=0.005),fast glucose(FG)MD=-0.14(-0.26,-0.03)(P=0.02),high-density lipoprotein cholesterol(HDL-C)MD=2.03(0.12,3.94)(P=0.04),triglycerides(TG)MD=-17.60(-34.76,-0.44)(P=0.04),total cholesterol(TC)MD=-9.38(-16.25,-2.51)(P=0.007),systolic blood pressure(SBP)MD=-7.18(-10.81,-3.55)(P=0.0001),diastolic blood pressure(DBP)MD=-2.93(-4.48,-1.37)(P=0.0002)and·VO2 maxMD=2.44(0.91,3.98)(P=0.0002).Resistance training or combined with low-intensity aerobic exercise had a significant effect only on systolic blood pressure MD=-8.81(-14.98,-2.63)(P=0.005)and fat mass%(FM%)MD=-3.06(-4.70,-1.42)(P=0.0002).Aerobic exercise and resistance training or combined with low-intensity aerobic exercise did not significantly affect body weight and body mass index.Conclusion:Our results suggest that aerobic exercise is the best way to improve cardiovascular risk factors in adult patients with MS.It has significant advantages in improving WC,FG,HDL-C,TG,TC,SBP,DBP and V·O2 max,which can effectively reduce the risk of cardiovascular disease.Resistance training or combined with low-intensity aerobic exercise only reduce SBP and FM%. |
| |
| Keywords: | metabolic syndrome cardiovascular risk aerobic exercise resistance training Me-ta analysis |
| 本文献已被 维普 等数据库收录！ |
|
