| 脑脊液中单纯疱疹病毒抗原检测和临床评价 |
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| 引用本文： | 高宗良,周农,陈贵海,王长青,王明丽,龚蕴贞,史百芬,李京培,曹慧.脑脊液中单纯疱疹病毒抗原检测和临床评价[J].河北北方学院学报(医学版),1994(3). |
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| 作者姓名： | 高宗良 周农 陈贵海 王长青 王明丽 龚蕴贞 史百芬 李京培 曹慧 |
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| 作者单位： | 安徽医科大学附属医院神经科
(高宗良，周农，陈贵海，王长青)，安徽医科大学微生物学教研室
(王明丽，龚蕴贞，史百芬，李京培)，安徽医科大学校医院(曹慧) |
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| 摘 要： | 本文采用ELISA双单克隆抗体夹心法检测14份拟诊为中枢神经系统病毒感染患者脑脊液(CSF)标本中单纯疱疹病毒(HSV)抗原。结果表明:有8份标本出现阳性,即约57％可测出HSV抗原。其中7份标本结果与间接ELISA检测CSF和血清HSV-Ⅰ～Ⅱ型抗体结果比较,两者有较好的一致性。提示ELISA双单克隆抗体夹心法检测临床标本中HSV抗原,具有简便、特异、敏感等优点,4h内即能获得检测结果,适用于HSV性脑炎(HSE)的早期诊断。
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| 关 键 词： | 单纯疱疹病毒 脑脊液 ELISA 脑炎 |
RAPID DETECTION OF HERPES SIMPLEX VIRUS ANTIGENS IN CSF OF PATIENTS WITH ENCEPHALITIS AND CLINIAL EVALUATION |
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| Gao Zhong-Liang.RAPID DETECTION OF HERPES SIMPLEX VIRUS ANTIGENS IN CSF OF PATIENTS WITH ENCEPHALITIS AND CLINIAL EVALUATION[J].Journal of Hebei North University:Medical Edition,1994(3). |
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| Authors: | Gao Zhong-Liang |
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| Institution: | Gao Zhong-LiangDepartment of neurology Afflitiated hospital of AnhuiMedical University,HeFei 230022 |
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| Abstract: | Herpes simplex virus(HSV) antigen in CSF was detected by use o f sandwich ELISA oftwo-monoclonal antibodies against HSV,Comparison ofthis methodwith that of indirection ELISA detection of IgG and IgM against HSVin CSF and serum showed that they had better consisteney,but former had many obvious advantages, such as much more rapid sensitive specific and cheeper. |
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| Keywords: | Herpes simplex virus ELISA Antigen CSF |
| 本文献已被 CNKI 等数据库收录！ |
