Biochemical activity of selenium and glutathione on country made liquor (CML) induced hepatic damage in rats |
| |
| Authors: | G Kumar G Sharmila Banu M Rajasekara Pandian |
| |
| Institution: | (1) Department of Biochemistry, Selvamm Arts & Science College, Namakkal;(2) Centre for Biotechnology, Muthay ammal College of Arts and Sciences, Kakkaveri, Rasipuram, 637408 Namakkal, Tamilnadu, India |
| |
| Abstract: | The serum and hepatic enzymes of rats were studied after exposed to country made liquor (CML) along with two chelating agents
(glutathione and Selenium). There was a significant increase in several serum enzyme levels (viz., aspartate transaminase,
alanine transaminase, alkaline phosphatase, sorbitol dehydrogenase, glutamate dehydrogenase, bilirubin) and decrease in various
hepatic enzymes (Succinic dehydrogenase, Glucose 6-phosphatase, 5'Nucleotiease, Acid phosphatase, Acid ribonuclease, Cytochrome
P-450) due to repeated administration of CML (2ml/100g of body weight). Results of this study revealed that the GSH and Se
could give a significant protective action in serum and hepatic enzymes of CML exposed rats. |
| |
| Keywords: | Serum and Hepatic enzymes CML Chelating agents Hepatoprotection |
| 本文献已被 SpringerLink 等数据库收录！ |
|
