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基于光诱导介电泳的微粒子操纵路径规划方法
引用本文:常严,朱晓璐,倪中华.基于光诱导介电泳的微粒子操纵路径规划方法[J].东南大学学报,2011(4):388-393.
作者姓名:常严  朱晓璐  倪中华
作者单位:[1]东南大学机械工程学院,南京211189 [2]东南大学江苏省微纳生物医疗器械设计与制造重点实验室,南京211189
基金项目:Foundation items: The National Natural Science Foundation of China (No. 91023024, 51175083), Scientific Research Foundation of Graduate School of Southeast University(No. YBJJ1020), Jiangsu Graduate Innovative Research Program ( No. CX10B_062Z).
摘    要:为实现基于光诱导介电泳的微粒子自动化操纵,设计了基于改进人工势场的缩微光图案路径规划方法.针对传统人工势场的局部极小问题,给出一种新的局部极小判别准则.在此基础上提出导引目标和点障碍相结合的方法来脱离局部极小点,并将改进后的人工势场算法集成于基于光诱导介电泳的微纳米生物粒子操纵平台中,进行微粒子操纵实验.结果表明,该方...

关 键 词:光诱导介电泳  人工势场  导引目标  点障碍

Path planning for light-induced dielectrophoretic manipulation of micro-particles
Chang Yan Zhu Xiaolu Ni Zhonghua.Path planning for light-induced dielectrophoretic manipulation of micro-particles[J].Journal of Southeast University(English Edition),2011(4):388-393.
Authors:Chang Yan Zhu Xiaolu Ni Zhonghua
Institution:Chang Yan Zhu Xiaolu Ni Zhonghua (School of Mechanical Engineering, Southeast University, Nanjing 211189, China) (Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing 211189, China)
Abstract:To realize automatic manipulation of micro-particles by light-induced dielectrophoresis (LDEP), a path-planning scheme based on the improved artificial potential field (APF) for micro light pattern movements is proposed. An algorithm combining guided target and point obstacle based on a new local minimum judging criterion is specially designed, which can solve the local minimum problems encountered by the traditional APF. Experiments of real-time particle manipulation based on this algorithm are implemented and the experimental results show that the proposed approach can overcome the local minimum problems of the traditional APF method, and it is validated to be highly stable for intensive particle obstacles during LDEP manipulation. Consequently, this method can realize real-time manipulation of micro-nano particles with safety, decrease the difficulty of manual manipulation, and thus improve the efficiency of manipulation of micro-particles.
Keywords:light-induced dielectrophoresis  artificial potential field  guided target  point obstacle
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