| 细胞内钙离子分布的四维可视化技术实现 |
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| 引用本文： | 陈继,宁钢民,肖桂凤,陶荣,郑筱祥.细胞内钙离子分布的四维可视化技术实现[J].科技通报,2005,21(5):564-567. |
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| 作者姓名： | 陈继 宁钢民 肖桂凤 陶荣 郑筱祥 |
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| 作者单位： | 浙江大学,生物医学工程学系,杭州,310027 |
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| 基金项目： | 国家自然科学基金资助项目(30170275) |
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| 摘 要： | 细胞内钙离子参与了许多重要的细胞生理功能,因此研究其三维空间分布和动态变化具有重要的生理意义。本文针对通过激光共聚焦显微镜获得的细胞内钙离子荧光图像,应用计算机可视化技术,提出了一种四维(空间和时间)可视化技术方法,用于描述钙离子在细胞内的三维空间分布及其随时间的变化。
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| 关 键 词： | 生物医学工程 胞内钙离子 四维可视化 科学计算可视化 |
| 文章编号： | 1001-7119（2005）05-0564-04 |
| 收稿时间： | 2004-03-12 |
| 修稿时间： | 2004年3月12日 |
Realization of 4D Visualization of Intracellular Ca2+ |
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| CHEN Ji,NING Gang-min,XIAO Gui-feng,TAO Rong,ZHENG Xiao-xiang.Realization of 4D Visualization of Intracellular Ca2+[J].Bulletin of Science and Technology,2005,21(5):564-567. |
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| Authors: | CHEN Ji NING Gang-min XIAO Gui-feng TAO Rong ZHENG Xiao-xiang |
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| Abstract: | Intracellular Ca2 regulates diverse physiological functions. The spatial distribution of intracellular calcium and its activity is a key to understand this point. This paper reported a novel system which provides 4D (space and time) visu- alization for the distribution of intracellular calcium. At first intracellular calcium fluorescence images by Laser Scanning Confocal Microscope with fixed time interval are acquired. For each time point, the scanning images are pre-processed, such as filter and registration. Then with these processed images, volume data of intracellular calcium are hybrid ren- dered. Finally, a series of hybrid rendering-outcomes are loaded in time sequence, thus the viewers can clearly observe the activity of calcium in the cell. |
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| Keywords: | biomedical engineering intracellular Ca2 4D visualization visualization in scientific computing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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