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| 人工神经网络法同时测定安痛定注射液中三组份含量 | |
| 引用本文： | 丁德荣,朱凤军,刘世庆.人工神经网络法同时测定安痛定注射液中三组份含量[J].金华职业技术学院学报,2001,1(3):42-44. |
| 作者姓名： | 丁德荣 朱凤军 刘世庆 |
| 作者单位： | 1. 湖南医科大学药学系,硕士,41000,长沙市 2. 浙江迪耳药业有限公司药物研究所,工程师,321000,金华市 3. 金华职业技术学院经贸学院,教授,321017,金华市 |
| 摘 要： | 目的：建立不经分离同时测定安痛定注射液中三组份含量的方法。方法：运用误差反向传播(BP)的人工神经网络法(ANN)并将人工神经网络法与标准法测得实际样品的结果进行比较。结果：该法测得模拟样品中氨基比林、安替比林、巴比妥的平均回收率分别为99．4％、100．6％、100．2％，相对标准偏差分别为2．0％、1.8％、1．7％，经t检验表明，两者无显著差异。结论：人工神经网络法可快速、准确地测定复方药物制剂多组份含量。 |
| 关 键 词： | 人工神经网络法 安痛定注射液 测定 氨基比林 安替比林 巴比妥 含量 解热镇痛药 |
| 修稿时间： | 2001年3月26日 |
Simultaneous Determination of Three Components in Antongding Injection by Artificial Neural Network |
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| Ding Delong Zhu Fengjun Liu Shiqing.Simultaneous Determination of Three Components in Antongding Injection by Artificial Neural Network[J].Journal of Jinhua College of Profession and Technology,2001,1(3):42-44. | |
| Authors: | Ding Delong Zhu Fengjun Liu Shiqing |
| Abstract: | In this paper,a new determination method was suggested and used for determining three com-ponents in Antongding injection without separation.All components in simulated samples and actual samples were determined by artificial neural network(ANN)based on error back-propagation(BP).The results of actual samples obtained by ANN were compared with those obtained by standard method.The average recovery and relative standard deviation of amidopyrine,phenazone,barbital obtained by ANN were99.4%,2.0%,100.6%,1.8%,100.2%,1.7%respectively.It was showed by t-test that there was no significant difference between the results of ANN and standard method.ANN can be applied to multicomponent analysis of compound pharmaceutical preparations.This method is rapid,accurate and precise. |
| Keywords: | Error back-propagation Artificial neutral network Standard method An-tongding injection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |