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Cinderella in Serum Protein Electrophoresis
Authors:Srinivas Narasimhachar Chakravarthy  Satish Ramanathan  Smitha Menon  Vijayakumar Valappil  Mathivanan Durairaj  Jayarani Arokia
Institution:1.Department of Laboratory Medicine,MIOT Hospitals,Manapakkam, Chennai,India
Abstract:Paraproteinemia is characterised by clonal proliferation of plasma cells. A common laboratory finding in paraproteinemia being a monoclonal peak in serum protein electrophoresis (M band). But there are factors which produce a peak similar to M spike in serum protein electrophoresis and these factors are known as pseudoparaproteins. This case report discusses a rare cause of pseudo M spike in a known case of autoimmune hemolytic anaemia due to administration of drug-Rituximab, a monoclonal antibody by itself.
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